CD98 Antibody (UM7F8) [Alexa Fluor® 532]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-Fr
Clone
UM7F8
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 532

Order Details

CD98 Antibody (UM7F8) [Alexa Fluor® 532] Summary

Immunogen
Molt 13 T cell line
Localization
Cell surface, cytoplasmic
Specificity
CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC3A2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD98 Antibody (UM7F8) [Alexa Fluor® 532]

  • 4F2
  • 4F2hc
  • 4T2HC
  • antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC
  • CD98 antigen
  • CD98 heavy chain
  • CD98
  • CD98HC
  • CH98hc
  • FRP-1
  • heavy chain
  • Lymphocyte activation antigen 4F2 large subunit
  • MDU1antigen defined by monoclonal 4F2, heavy chain
  • monoclonal 44D7
  • NACAE4F2 cell-surface antigen heavy chain
  • SLC3A2
  • solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CD98 Antibody (NBP2-34506AF532) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34506AF350
Alexa Fluor 405 NBP2-34506AF405
Alexa Fluor 488 NBP2-34506AF488
Alexa Fluor 532 NBP2-34506AF532
Alexa Fluor 594 NBP2-34506AF594
Alexa Fluor 647 NBP2-34506AF647
Alexa Fluor 700 NBP2-34506AF700
Alexa Fluor 750 NBP2-34506AF750
Allophycocyanin NBP2-34506APC
Allophycocyanin/Cy7 NBP2-34506APCCY7
Biotin NBP2-34506B
DyLight 350 NBP2-34506UV
DyLight 405 NBP2-34506V
DyLight 488 NBP2-34506G
DyLight 550 NBP2-34506R
DyLight 594 NBP2-34506DL594
DyLight 650 NBP2-34506C
DyLight 680 NBP2-34506FR
DyLight 755 NBP2-34506IR
FITC NBP2-34506F
HRP NBP2-34506H
Janelia Fluor 549 NBP2-34506JF549
Janelia Fluor 646 NBP2-34506JF646
PE NBP2-34506PE
PE/Atto594 NBP2-34506PEATT594
PE/Cy5.5 NBP2-34506PECY55
PE/Cy7 NBP2-34506PECY7

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Bioinformatics Tool for CD98 Antibody (NBP2-34506AF532)

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Blogs on CD98.

CD98 - cell surface glycoprotein that promotes cell adhesion, growth, and survival
CD98 is a heterodimeric glycoprotein that contains an 80 kDa heavy chain and a 40 kDa light chain. The CD98 heavy chain is also known as the 4F2 antigen heavy chain or FRP-1, and it is encoded by the SLC3A2 gene. The CD98 heavy chain is capable of...  Read full blog post.

xCT: Friend or Foe?
There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has...  Read full blog post.

Glutathione and xCT: Chemoresistance in Tumor Cells
Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in membrane t...  Read full blog post.

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Bioinformatics

Gene Symbol SLC3A2