CD7 Antibody (C21-Q)

Immunohistochemistry-Paraffin: CD7 Antibody (C21-Q) [NBP1-79080] - CD7 expression in T-lymphocytes of the palatine tonsil. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti-CD7 monospecific clonal antibody.

Immunohistochemistry-Paraffin: CD7 Antibody (C21-Q) [NBP1-79080] - CD7 expression in T-lymphocytes of the lymph node. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with anti-CD7 monospecific clonal antibody.

• Reactivity: Hu
• Applications: IHC
• Clone: C21-Q
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

CD7 Antibody (C21-Q) Summary

• Description: This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
• Immunogen: Peptide derived from C-terminal region of human CD7. Antibody recognizes the epitope between Val221 - Gln238.
• Epitope: Val221 - Gln238
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CD7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:300

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 20mM Tris-HCl (pH 8.0) and 20mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Alternate Names for CD7 Antibody (C21-Q)

• CD7 antigen (p41)
• CD7 antigen
• CD7 molecule
• CD7
• GP40T-cell surface antigen Leu-9
• LEU-9
• T-cell antigen CD7
• T-cell leukemia antigen
• Tp40
• TP41
• TP41p41 protein

Background

CD7, also known as gp40, is a 40 kD type I transmembrane glycoprotein member of the immunoglobulin superfamily. It is found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD7
• Uniprot:
  • P09564(Human)