CD11c Antibody (CA11.6A1) Summary
Made to Dog CD11c
Dendritic Cell Marker
Recognizes the canine CD11c cell surface antigen, a member of the alpha integrin family. Canine CD11c is expressed by monocytes, granulocytes and by dendritic cells.
Tissue culture supernatant
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Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
This product is unpurified. The exact concentration of antibody is not quantifiable.
Tissue culture supernatant
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.
Alternate Names for CD11c Antibody (CA11.6A1)
- 95 alpha chain
- 95, alpha subunit
- CD11 antigen-like family member C
- CD11c antigen
- CD11Cleu M5, alpha subunit
- Integrin alpha X
- integrin alpha-X
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- integrin, alpha X (complement component 3 receptor 4 subunit)
- Leu M5
- Leukocyte adhesion glycoprotein p150
- Leukocyte adhesion receptor p150
- leukocyte surface antigen p150
- myeloid membrane antigen, alpha subunit
- p150 95 integrin alpha chain
- p150,95 alpha
CD11c (integrin alpha X chain protein) combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. The CD11c antigen is a marker for hairy cell leukemia.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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