CD11c Antibody (CA11.6A1)

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Product Details

Summary
Reactivity CaSpecies Glossary
Applications Flow, IHC, IHC-Fr, IP
Clone
CA11.6A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CD11c Antibody (CA11.6A1) Summary

Immunogen
Made to Dog CD11c
Marker
Dendritic Cell Marker
Specificity
Recognizes the canine CD11c cell surface antigen, a member of the alpha integrin family. Canine CD11c is expressed by monocytes, granulocytes and by dendritic cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGAX
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10-1:500
Application Notes
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.
Reviewed Applications
Read 1 Review rated 2
using
NB100-65291 in the following applications:

Reactivity Notes

Reacts with: Hooded Seal, Raccoon.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
0.1% Sodium Azide
Purity
Tissue culture supernatant

Alternate Names for CD11c Antibody (CA11.6A1)

  • 95 alpha chain
  • 95
  • 95, alpha subunit
  • CD11 antigen-like family member C
  • CD11c antigen
  • CD11c
  • CD11Cleu M5, alpha subunit
  • Integrin alpha X
  • integrin alpha-X
  • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
  • integrin, alpha X (complement component 3 receptor 4 subunit)
  • ITGAX
  • Leu M5
  • Leukocyte adhesion glycoprotein p150
  • Leukocyte adhesion receptor p150
  • leukocyte surface antigen p150
  • myeloid membrane antigen, alpha subunit
  • p150 95 integrin alpha chain
  • p150,95 alpha
  • SLEB6

Background

CD11c (integrin alpha X chain protein) combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. The CD11c antigen is a marker for hairy cell leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD11c Antibody (NB100-65291) (0)

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Review for CD11c Antibody (NB100-65291) (1) 21

Average Rating: 2
(Based on 1 review)
We have 1 review tested in 1 species: Feline.
We have 1 review tested in 1 application: IHC-Fr.

Reviews using NB100-65291:
Filter by Applications
IHC-Fr
(1)
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Filter by Species
Feline
(1)
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Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen CD11c NB100-65291
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reviewed by:
Anonymous
IHC-Fr Feline 12/08/2017
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Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedOptic nerve
SpeciesFeline
Lot100415

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FAQs for CD11c Antibody (NB100-65291) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on CD11c.

CD11b: Marker for a New Type of B Cell that Participates in Cell-Mediated Immunity
Think B lymphocytes just produce antibodies? Think again! Although, of course, B cells are vital for the humoral immune response, many studies in recent years have begun to uncover antibody-independent actions of B cells: regulating T cells and thus a...  Read full blog post.

Adhesion Receptor Molecule CD11b/c is the Point of Entry for many Infectious Diseases
Pathogenic microorganisms utilize a variety of cell surface receptors to gain entry into host cells and to bypass the natural defense mechanisms. One of the most prominent receptors used in this fashion is the leukocyte adhesion receptor CD11b/c. This...  Read full blog post.

CD11b/CD18 and Neutrophil-Epithelial Interactions as Targets for Anti-Inflammatory Therapies
The beta-2 integrins, a family of four cell surface transmembrane glycoproteins expressed only on leukocytes, include CD11a/CD18, CD11b/CD18, CD11c/CD18, and CD11d/CD18. They consist of a common beta subunit (CD18) and homologous alpha subunits (CD11a...  Read full blog post.

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Recent Reviews

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5
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2
1
1
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Anonymous
12/08/2017
Application: IHC-Fr
Species: Feline

Bioinformatics

Gene Symbol ITGAX
Entrez