CCR6 Antibody

Images

 
Immunohistochemistry-Paraffin: CCR6 Antibody [NLS356] - IHC staining of human tonsil using this antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CCR6 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human CCR6.
Specificity
Human CCR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR6
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 2 ug/ml-9 ug/ml
Positive Control
CCR6 Lysate (NBL1-08893)
Reviewed Applications
Read 1 Review rated 3
using
NLS356 in the following application:

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Monkey (89%), Opossum (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCR6 Antibody

  • BN-1
  • CC-CKR-6
  • CCR6
  • CCR-6
  • CD196 antigen
  • CD196
  • chemokine (C-C motif) receptor 6
  • CKR-L3G-protein coupled receptor 29
  • CKRL3LARC receptor
  • CMKBR6STRL22
  • DRY6
  • GPR29
  • GPR29C-C CKR-6
  • GPR-CY4
  • GPRCY4DRY-6
  • lymphocyte, 22
  • STRL22

Background

CCR6 is a Chemokine Receptor that is activated by MIP3alpha/Larc binding. CCR6 has been shown to be upregulated in psoriatic skin. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells but not in natural killer cells, monocytes, or granulocytes from spleen, lymph node, appendix, and fetal liver. ESTs have been isolated from liver/spleen, lymph, and fetal lung/testis/B cell libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR6 Antibody (NLS356) (0)

There are no publications for CCR6 Antibody (NLS356).
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Review for CCR6 Antibody (NLS356) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NLS356:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
IHC-P Human 05/20/2016
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample Testedskin
SpeciesHuman
Lot6246

Product General Protocols

View specific protocols for CCR6 Antibody (NLS356): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCR6 Antibody (NLS356). (Showing 1 - 1 of 1 FAQ).

  1. I am looking for an anti-bovine CCR6 antibody and I see your antibody below was raised in goat so may cross react. Do you know if it can be used in cattle for flow cytometry? CCR6 Antibody (NB100-713)
    • Unfortunately, the species that the antibody is made in is no indicator of the species it will react to. In this case, the immunogen for NB100-713 shares just 57% similarity with bovine CCR6, so this antibody will almost certainly not cross-react with bovine. In this case, the immunogens for NLS356 and NBP1-88565 shares 79% similarity with bovine and have the highest chance of cross-reactivity of any antibodies we carry, although this is still below the 85% that we generally prefer to recommend for cross-reactivity. These are the best two we currently have for your species.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional Array Products

Bioinformatics Tool for CCR6 Antibody (NLS356)

Discover related pathways, diseases and genes to CCR6 Antibody (NLS356). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CCR6 Antibody (NLS356)

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Pathways for CCR6 Antibody (NLS356)

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Research Areas for CCR6 Antibody (NLS356)

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Blogs on CCR6

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Recent Reviews

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Anonymous
05/20/2016
Application: IHC-P
Species: Human

Bioinformatics

Gene Symbol CCR6
Entrez
Uniprot