CCR6 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	1235
Alternate Names	BN-1 CC-CKR-6 CCR6 CCR-6 CD196 antigen CD196 chemokine (C-C motif) receptor 6 CKRL3 CKR-L3 CKR-L3G-protein coupled receptor 29 CKRL3LARC receptor CMKBR6 CMKBR6STRL22 DRY6 GPR29 GPR29C-C CKR-6 GPRCY4 GPR-CY4 GPRCY4DRY-6 lymphocyte, 22 STRL22

Research Areas for CCR6

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
GPCR
Immunology
Innate Immunity
Signal Transduction