Human CCL20/MIP-3 alpha Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human CCL20/MIP-3 alpha Quantikine ELISA Kit Summary

Background
The Quantikine Human MIP-3 alpha Immunoassay is a 4.5 hour solid phase ELISA designed to measure MIP-3 alpha levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human MIP-3 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring human MIP-3 alpha showed linear curves that were parallel to the s...tandard curves obtained using the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MIP-3 alpha.
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Specificity
Natural and recombinant human MIP-3 alpha
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL20

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DM3A00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL20/MIP-3 alpha Quantikine ELISA Kit

  • beta chemokine exodus-1
  • Beta-chemokine exodus-1
  • CC chemokine LARC
  • C-C motif chemokine 20
  • CCL20
  • chemokine (C-C motif) ligand 20
  • CKb4
  • exodus-1
  • LARC
  • LARCLiver and activation-regulated chemokine
  • MIP3 alpha
  • MIP-3 alpha
  • MIP-3a
  • MIP-3-alpha
  • MIP3AMacrophage inflammatory protein 3 alpha
  • SCYA20Small-inducible cytokine A20
  • small inducible cytokine subfamily A (Cys-Cys), member 20
  • ST38

Background

CCL20, also known as MIP-3 alpha, is a chemokine that plays an important role in dendritic cell trafficking and recruitment and activation of T cells. It is upregulated in monocytes, T cells, endothelial cells, epithelial cells, and fibroblasts following inflammatory stimulation. CCL20 signals through CCR6 which is expressed on memory T cells, B cells and bone marrow-derived dendritic cells.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL20/MIP-3 alpha (DM3A00)(41)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Filter By Species
Human
(41)
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Showing Publications 1 - 10 of 41. Show All 41 Publications.
Publications using DM3A00 Applications Species
O Ibidapo-Ob, S Stengel, N Köse-Vogel, S Quickert, PA Reuken, M Busch, M Bauer, A Stallmach, T Bruns Mucosal-associated invariant T cells redistribute to the peritoneal cavity during spontaneous bacterial peritonitis and contribute to peritoneal inflammation Cell Mol Gastroenterol Hepatol, 2020;0(0):. 2020 [PMID: 31954178] (Human) Human
K Furue, T Ito, Y Tanaka, A Hashimoto-, M Takemura, M Murata, M Kido-Nakah, G Tsuji, T Nakahara, M Furue The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients Int J Mol Sci, 2020;21(2):. 2020 [PMID: 31936670] (Human) Human
SJ Park, H Kim, SH Kim, EH Joe, I Jou Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells Acta Neuropathol Commun, 2019;7(1):149. 2019 [PMID: 31530290] (Human) Human
K Furue, T Ito, Y Tanaka, A Yumine, A Hashimoto-, M Takemura, M Murata, K Yamamura, G Tsuji, M Furue Cyto/chemokine profile of in vitro scratched keratinocyte model: Implications of significant upregulation of CCL20, CXCL8 and IL36G in Koebner phenomenon J. Dermatol. Sci., 2019;0(0):. 2019 [PMID: 31010609] (Human) Human
PM Schlievert, MP Cahill, BS Hostager, AJ Brosnahan, AJ Klingelhut, FA Gourronc, GA Bishop, DYM Leung Staphylococcal Superantigens Stimulate Epithelial Cells through CD40 To Produce Chemokines MBio, 2019;10(2):. 2019 [PMID: 30890614] (Human) Human
P Chen, Z Zhong, H Jiang, H Chen, J Lyu, L Zhou Th17-associated cytokines multiplex testing indicates the potential of macrophage inflammatory protein-3 alpha in the diagnosis of biliary atresia Cytokine, 2019;116(0):21-26. 2019 [PMID: 30684914] (Human) Human
L Wang, D Zhou, H Ren, Y Chen Effects of modified FOLFOX-6 chemotherapy on cellular immune function in patients with gastric cancer Oncol Lett, 2018;15(6):8635-8640. 2018 [PMID: 29805598] (Human) Human
G Lu, X Zhang, L Shen, Q Qiao, Y Li, J Sun, J Zhang CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy PLoS ONE, 2017;12(5):e0178352. 2017 [PMID: 28552941] (Human) Human
X Ye, R Wang, R Bhattachar, D Boulbes, F Fan, L Xia, H Adoni, NJ Ajami, MC Wong, DP Smith, JF Petrosino, S Venable, W Qiao, V Baladanday, DM Maru, LM Ellis Fusobacterium nucleatum subspecies animalis influences pro-inflammatory cytokine expression and monocyte activation in human colorectal tumors Cancer Prev Res (Phila), 2017;0(0):. 2017 [PMID: 28483840] (Human) Human
Valentina Cecchinato Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization J. Immunol, 2016;0(0):. 2016 [PMID: 27895171] (Human) Human
Show All 41 Publications.

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Product General Protocols

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FAQs for CCL20/MIP-3 alpha (DM3A00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DM3A00

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Bioinformatics

Gene Symbol CCL20