CCR5 Antibody

Images

 
Western Blot: CCR5 Antibody [NBP2-31374] - Western blot image of anti-CCR5 antibody. Whole cell protein from Daudi (lane 1), K562 (lane 2) and THP-1 (lane 3) cell lines were separated by SDS-PAGE and protein transfered ...read more
Immunohistochemistry-Paraffin: CCR5 Antibody [NBP2-31374] - IHC-P analysis of CCR5 protein in a section of malignant stromal tumor of small bowel from human using CCR5 antibody at a concentration of 5 ug/ml.
Western Blot: CCR5 Antibody [NBP2-31374] - WB detection of CCR5 partial recombinant protein by using CCR5 antibody at a concentration of 0.5 ug/ml
Simple Western: CCR5 Antibody [NBP2-31374] - Simple Western lane view shows a specific band for CCR5 in 0.5 mg/ml of MCF-7 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation ...read more

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, Simple Western, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CCR5 Antibody Summary

Immunogen
Partial recombinant protein made to an N-terminal portion of the human CCR5 protein (between amino acids 1-350) [UniProt P51681]
Localization
Multi-pass membrane protein with extra-cellular and cytoplasmic domains
Predicted Species
Primate (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR5
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
  • Simple Western 1:50
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Application Notes
In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size.
Positive Control
CCR5 Lysate (H00001234-T01)
CCR5 Lysate (H00001234-T04)
CCR5 Lysate (NBP2-09009)
Reviewed Applications
Read 1 Review rated 5
using
NBP2-31374 in the following applications:

Publications
Read Publication using NBP2-31374.

Reactivity Notes

Immunogen has 86% homology to bovine.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for CCR5 Antibody

  • C-C CKR-5
  • C-C motif chemokine receptor 5 A159A
  • CCCKR5
  • CC-CKR-5FLJ78003
  • CCR5
  • CCR-5
  • CD195 antigen
  • CD195
  • chemokine (C-C motif) receptor 5
  • chemokine receptor CCR5
  • chemr13
  • CKR5
  • CKR-5
  • HIV-1 fusion coreceptor
  • IDDM22CMKBR5C-C chemokine receptor type 5

Background

The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB172
Species: Hu
Applications: Flow, IHC, CyTOF-ready, Neut
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP1-48337
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
MAB145
Species: Hu
Applications: Flow, CyTOF-ready
MAB155
Species: Hu
Applications: Flow, IHC, CyTOF-ready, Neut
MAB160
Species: Hu
Applications: Flow, IHC, CyTOF-ready, Neut
NBP1-49045
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
MAB1567
Species: Hu
Applications: Flow, CyTOF-reported
NBP2-37856
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP1-86564
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP2-31374
Species: Hu, Pm
Applications: WB, Simple Western, IHC, IHC-P

Publications for CCR5 Antibody (NBP2-31374)(1)

We have publications tested in 1 application: IHC.


Filter By Application
IHC
(1)
All Applications
Filter By Species
All Species

Review for CCR5 Antibody (NBP2-31374) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.
We have 1 review tested in 1 application: IHC-P.

Reviews using NBP2-31374:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Other
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin CCR5 NBP2-31374
Enlarge
reviewed by:
Maria Cecilia Marcondes
IHC-P Other 06/01/2015
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedBrain
SpeciesOther

Product General Protocols

View specific protocols for CCR5 Antibody (NBP2-31374): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for CCR5 Antibody (NBP2-31374) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional CCR5 Products

Bioinformatics Tool for CCR5 Antibody (NBP2-31374)

Discover related pathways, diseases and genes to CCR5 Antibody (NBP2-31374). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CCR5 Antibody (NBP2-31374)

Discover more about diseases related to CCR5 Antibody (NBP2-31374).
 

Pathways for CCR5 Antibody (NBP2-31374)

View related products by pathway.

PTMs for CCR5 Antibody (NBP2-31374)

Learn more about PTMs related to CCR5 Antibody (NBP2-31374).
 

Research Areas for CCR5 Antibody (NBP2-31374)

Find related products by research area.

Blogs on CCR5

There are no specific blogs for CCR5, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Maria Cecilia Marcondes
06/01/2015
Application: IHC-P
Species: Other

Bioinformatics

Gene Symbol CCR5
Entrez
Uniprot