Western Blot: CCR5 Antibody [NBP2-31374] - Western blot image of anti-CCR5 antibody. Whole cell protein from Daudi (lane 1), K562 (lane 2) and THP-1 (lane 3) cell lines were separated by SDS-PAGE and protein transfered ...read more
Immunohistochemistry-Paraffin: CCR5 Antibody [NBP2-31374] - IHC-P analysis of CCR5 protein in a section of malignant stromal tumor of small bowel from human using CCR5 antibody at a concentration of 5 ug/ml.
Western Blot: CCR5 Antibody [NBP2-31374] - WB detection of CCR5 partial recombinant protein by using CCR5 antibody at a concentration of 0.5 ug/ml
Simple Western: CCR5 Antibody [NBP2-31374] - Simple Western lane view shows a specific band for CCR5 in 0.5 mg/ml of MCF-7 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation ...read more
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.05% Sodium Azide
Protein A purified
Alternate Names for CCR5 Antibody
C-C motif chemokine receptor 5 A159A
chemokine (C-C motif) receptor 5
chemokine receptor CCR5
HIV-1 fusion coreceptor
IDDM22CMKBR5C-C chemokine receptor type 5
The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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