CCL17/TARC Antibody - Azide and BSA Free

• Reactivity: Hu
• Applications: WB, ELISA, Func
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

CCL17/TARC Antibody - Azide and BSA Free Summary

• Description: Novus Biologicals Rabbit CCL17/TARC Antibody - Azide and BSA Free (NBP1-40991) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant human CCL17
• Specificity: This antibody specifically recognises human CCL17, otherwise known as TARC (thymus and activation-regulated chemokine), a member of the intercrine beta (chemokine CC) family, predominantly produced by thymic dendritic cells, which specifically acts as a chemotactic factor for T cells, and signals through binding to the CCR4 receptor.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCL17
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Functional
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: IgG purified

Alternate Names for CCL17/TARC Antibody - Azide and BSA Free

• ABCD-2
• CC chemokine TARC
• C-C motif chemokine 17
• CCL17
• chemokine (C-C motif) ligand 17
• MGC138273
• SCYA17
• SCYA17MGC138271
• small inducible cytokine subfamily A (Cys-Cys), member 17
• Small-inducible cytokine A17
• T cell-directed CC chemokine
• TARC
• TARCA-152E5.3
• Thymus and activation-regulated chemokine

Background

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCL17
• Entrez:
  • 6361(Human)
• Uniprot:
  • Q92583()
  • Q92583()