CBX3 Antibody

Images

 
Immunohistochemistry: CBX3 Antibody [NB100-41429] - Sample: FFPE section of human ovarian carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-CBX3 used at a dilution of 1:5,000 ...read more
Proximity Ligation Assay: CBX3 Antibody [NB100-41429] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human ATM (NB100-271) and rabbit anti-human CBX3 (NB100-41429). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: CBX3 Antibody [NB100-41429] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human HP1-beta (NB100-79774) and rabbit anti-human CBX3 (NB100-41429). Image merged from DAPI (2ms) ...read more
Proximity Ligation Assay: CBX3 Antibody [NB100-41429] - Secondary-conjugate Duolink In Situ PLA in MCF-7. goat anti-human POLR2A (NBP2-14859) and rabbit anti-human CBX3 (NB100-41429). Image merged from DAPI (2ms), ...read more
Immunoprecipitation: CBX3 Antibody [NB100-41429] - Detection of Human CBX3 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P, IP, PLA, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

       

Order Details

CBX3 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CBX3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate
  • Proximity Ligation Assay 1:1000-1:10000
Positive Control
CBX3 Lysate (NBL1-08748)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Notes

This anitbody can be used as the primary antibody in a PLA assay with the following as complementing antibodies:NB100-322, NB100-381, NB100-2350

Alternate Names for CBX3 Antibody

  • chromobox homolog 3 (Drosophila HP1 gamma)
  • chromobox homolog 3
  • chromobox protein homolog 3
  • Drosophila)
  • HECH
  • Heterochromatin protein 1 homolog gamma
  • heterochromatin protein HP1 gamma
  • heterochromatin-like protein 1
  • HP1 gamma homolog
  • HP1 gamma
  • HP1-GAMMA
  • Modifier 2 protein

Background

CBX3 (chromobox protein homolog 3), also known as HP1gamma (heterochromatin protein 1 homolog gamma), is one of 3 isoforms of HP1 that binds heterochromatin and functions as a structural adaptor to stabilize and organize macromolecular complexes with nucleosomes for higher chromatin structure. All of the HP1 isoforms possess a chromodomain and chromoshadow domain and associate with methylated histones that mediate transcriptional repression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for CBX3 Antibody (NB100-41429)

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Bioinformatics

Gene Symbol CBX3
Entrez
Uniprot