Carbonic Anhydrase IV/CA4 Antibody (039) [DyLight 650]

• Reactivity: Hu
• Applications: ELISA, Flow, IHC
• Clone: 039
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 650

Carbonic Anhydrase IV/CA4 Antibody (039) [DyLight 650] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase IV/CA4 (Accession#: NP_000708.1; Met1-Lys283).
• Specificity: No cross-reactivity in ELISA with:
  
  Human CA2
  Human CA3
  Human CA5A
  Human CA5B
  Human CA8
  Human CA9
  Human CA10
  Human CA12
  Human CA13
  Human CA14
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CA4
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Carbonic Anhydrase IV/CA4 Antibody (039) [DyLight 650]

• CA4
• CAIV
• CA-IV
• Car4
• Carbonate dehydratase IV
• carbonic anhydrase 4
• Carbonic Anhydrase IV
• carbonic anhydrase IVRP17
• carbonic dehydratase IV
• EC 4.2.1.1
• retinitis pigmentosa 17 (autosomal dominant)
• RP17

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CA4