Cadherin-16 Antibody (SPM594) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, RbSpecies Glossary
Applications IHC-P
Clone
SPM594
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Cadherin-16 Antibody (SPM594) [Biotin] Summary

Immunogen
Recombinant human CDH16 protein
Localization
Cell Surface with some cytoplasmic
Specificity
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CDH16
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody shomld be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cadherin-16 Antibody (SPM594) [Biotin]

  • cadherin 16, KSP-cadherin
  • cadherin-16
  • Kidney-specific cadherin
  • KSP-cadherin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CDH16