Beta Ig-h3/TGFBI Antibody

ELISA: Beta Ig-h3/TGFBI Antibody [30950002]

Product Discontinued

Beta Ig-h3/TGFBI Antibody Summary

• Immunogen: This antibody is specific for the Middle Region of the target protein.
• Specificity: This product is specific for Human TGFBI.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TGFBI
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: This antibody is useful in ELISA.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for Beta Ig-h3/TGFBI Antibody

• beta IGH3
• beta IG-H3
• BIGH3EBMD
• CDB1
• CDG2
• CDGG1transforming growth factor, beta-induced, 68kD
• CSD
• CSD1
• CSD2
• CSD3
• Kerato-epithelin
• LCD1
• RGD-CAP
• RGD-containing collagen-associated protein
• TGFBI
• TGFBIP
• transforming growth factor, beta-induced, 68kDa
• transforming growth factor-beta-induced protein ig-h3

Background

TGFBI, also known as BIGH3 and betaig-h3, is an extracellular matrix protein induced by transforming growth factor (TGF)-beta 1. TGFBI protein is involved in cell growth, cell differentiation, wound healing and cell adhesion. In addition, some missense mutations of TGFBI were identified in families affected with human autosomal dominant corneal dystrophies. BIGH3 gene encodes for a 683 amino-acid protein containing an RGD motif and four internal repeated domains which have highly conserved sequences founded in several species (Fasciclin domain). Clone k1H12, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TGFBI protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Beta Ig-h3/TGFBI Antibody (30950002)(2)

Publications using 30950002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: TGFBI
• Uniprot:
  • Q15582()