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3409-BG) was serially diluted and captured by Mouse Anti-Human beta IG‑H3 Monoclonal Antibody (Catalog # MAB2935) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human beta IG‑H3 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2935) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
TGFBI encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq]