beta-Catenin Antibody (12F7) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ch, PmSpecies Glossary
Applications WB, Flow, Flow-IC, ICC/IF, IHC, IHC-P, ICC/IF
Clone
12F7
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 750

beta-Catenin Antibody (12F7) [Alexa Fluor® 750] Summary

Immunogen
Recombinant chicken beta Catenin fused to maltose binding protein. [UniProt# O42486]
Localization
Nucleus, Cytoplasm, Cytoskeleton, Adherens junction, Centrosome, Spindle pole.
Marker
Epithelial Cell Marker, Adherens Junction Marker
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CTNNB1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Flow (Intracellular)
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for beta-Catenin Antibody (12F7) [Alexa Fluor® 750]

  • bCatenin
  • beta 1 (88kD)
  • beta-Catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin beta-1
  • CTNNB
  • CTNNB1
  • DKFZp686D02253
  • FLJ25606
  • FLJ37923

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for beta-Catenin Antibody (NBP1-54467AF750) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-54467AF350
Alexa Fluor 405 NBP1-54467AF405
Alexa Fluor 488 NBP1-54467AF488
Alexa Fluor 532 NBP1-54467AF532
Alexa Fluor 594 NBP1-54467AF594
Alexa Fluor 647 NBP1-54467AF647
Alexa Fluor 700 NBP1-54467AF700
Alexa Fluor 750 NBP1-54467AF750
Biotin NBP1-54467B
DyLight 350 NBP1-54467UV
DyLight 405 NBP1-54467V
DyLight 488 NBP1-54467G
DyLight 550 NBP1-54467R
DyLight 594 NBP1-54467DL594
DyLight 650 NBP1-54467C
DyLight 680 NBP1-54467FR
DyLight 755 NBP1-54467IR
FITC NBP1-54467F
HRP NBP1-54467H
Janelia Fluor 549 NBP1-54467JF549
Janelia Fluor 646 NBP1-54467JF646

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Bioinformatics Tool for beta-Catenin Antibody (NBP1-54467AF750)

Discover related pathways, diseases and genes to beta-Catenin Antibody (NBP1-54467AF750). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for beta-Catenin Antibody (NBP1-54467AF750)

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Pathways for beta-Catenin Antibody (NBP1-54467AF750)

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Research Areas for beta-Catenin Antibody (NBP1-54467AF750)

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Blogs on beta-Catenin.

Stemness is responsible for onset and metastasis of colorectal cancer
By Jamshed Arslan, Pharm. D., PhD. Colorectal cancer stem cells are a rare subpopulation of colorectal cancer cells that can self-renew and initiate and sustain tumor growth when transplanted into an animal host.1,2 C...  Read full blog post.

The role of Wnts in neuroinflammation
By Michalina Hanzel, PhDThe multifaceted roles of the Wnt family of glycoproteins have been extensively characterized throughout embryonic development and adult homeostasis. The highly conserved, cell- and tissue- s...  Read full blog post.

Stemness for Surviving Hypoxia: TGF-beta/Smad Signaling in Multiple Myeloma
By Jamshed Arslan Pharm.D. Multiple myeloma (MM) is a cancer of antibody-producing plasma cells. The bone marrow (BM) of MM patients is hypoxic, and MM cells overexpress many cancerous genes that are regulated by hy...  Read full blog post.

Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...  Read full blog post.

CD63: is it pro-metastatic or anti-metastatic?
CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several cellular signaling cascades along with acting as TIMP1 receptor. It is expressed by activated platelets, monocytes,...  Read full blog post.

Notch1 - A multifunctional transmembrane receptor
Notch1 is a member of the Notch family of Type 1 single-pass transmembrane proteins that share an extracellular domain of multiple epidermal growth factor-like (EGF) repeats. Notch family members play key roles in a variety of developmental process...  Read full blog post.

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Bioinformatics

Gene Symbol CTNNB1