beta-Catenin Products

Antibodies
beta-Catenin Antibody [Unconj ...
beta-Catenin Antibody [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ChIP, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
beta-Catenin Antibody
beta-Catenin Antibody
Species: Hu, Mu, Rt, Ca, Fe, Rb, Ze, Po, Bv, Ch, RM, Sh, Xp
Applications: WB, Flow, Func, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
ELISA Kits
Human Total beta-Catenin DuoS ...
Human Total beta-Catenin DuoSet IC...
DYC1329-2
Species: Hu
Applications: ELISA
Conjugate Catalog # Availability Size Price
Lysates
beta-Catenin Overexpression L ...
beta-Catenin Overexpression Lysate
NBL1-09577
Species: Hu
Applications: WB
Proteins
beta-Catenin Recombinant Prot ...
beta-Catenin Recombinant Protein A...
NBP2-61628PEP
Species: Hu
Applications: AC
Recombinant Human beta-Cateni ...
Recombinant Human beta-Catenin GST...
H00001499-P01
Species: Hu
Applications: WB, ELISA, MA, AP
Recombinant Human beta-Cateni ...
Recombinant Human beta-Catenin His...
NBP3-18198
Species: Hu
Applications: PAGE, Bioactivity

Description

The protein encoded by the beta Catenin gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs arenecessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion betweencells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contactinhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this proteinbinds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this geneare a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.

Bioinformatics

Entrez Mouse
Human
Chicken
Rat
Uniprot Human
Human
Human
Chicken
Human
Human
Mouse
Rat
Alternate Names
  • beta 1 (88kD)
  • beta-catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin beta-1
  • CTNNB
  • DKFZp686D02253
  • FLJ25606
  • FLJ37923

Research Areas for beta-Catenin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Extracellular Matrix
Neuroscience
Phospho-Specific
Stem Cell Signaling Pathway
Wnt Signaling Pathway