Apelin Antibody - BSA Free

Immunohistochemistry: Apelin Antibody - BSA Free [NBP3-48129] - Immunohistochemistry of paraffin-embedded mouse heart tissue using (anti- Apelin antibody) at dilution of 1:200

• Reactivity: Hu, Mu, Rt
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Apelin Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Apelin Antibody - BSA Free (NBP3-48129) is a polyclonal antibody validated for use in IHC and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: apelin. (Uniprot# Q9ULZ1)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APLN
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:50-1:500

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Apelin Antibody - BSA Free

• AGTRL1 ligand
• AGTRL1 Lligand
• APEL
• Apelin
• apelin, AGTRL1 ligand
• APJ endogenous ligand
• APLN
• XNPEP2

Background

Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1. Apelin and APJ are ubiquitously expressed in peripheral tissues, with highest levels reported for heart and lungs, as well several regions within the central nervous system. The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ; the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates; more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, by influencing AVP release and drinking behavior. In the cardiovascular system several actions of Apelin have been described, including endothelium-dependent vasodilatation, vasoconstriction through direct action on smooth muscle and positive inotropism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APLN