Ghrelin Antibody (883622)


Ghrelin was detected in immersion fixed frozen sections of mouse stomach using Rat Anti-Human/Mouse Ghrelin Monoclonal Antibody (Catalog # MAB8200) at 10 µg/mL overnight at 4 °C. Tissue was stained using the more
Ghrelin was detected in immersion fixed paraffin-embedded sections of human stomach using Rat Anti-Human/Mouse Ghrelin Monoclonal Antibody (Catalog # MAB8200) at 15 µg/mL overnight at 4 °C. Tissue was stained using more

Product Details

Reactivity Hu, MuSpecies Glossary
Applications IHC

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Ghrelin Antibody (883622) Summary

E. coli-derived recombinant mouse Obestatin/Ghrelin prepropeptide
Accession # Q9EQX0
Detects mouse and human Ghrelin/Obestatin prepropeptide in ELISA. Detects human Ghrelin peptides (acylated and de-acylated) in ELISA.
Protein A or G purified from hybridoma culture supernatant
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunohistochemistry 8-25 ug/mL
Read Publications using
MAB8200 in the following applications:

  • ICC
    1 publication
  • IHC
    5 publications

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Ghrelin Antibody (883622)

  • appetite-regulating hormone
  • Ghrelin
  • ghrelin/obestatin preprohormone
  • ghrelin/obestatin prepropeptide
  • GHRL
  • Growth hormone secretagogue
  • Growth hormone-releasing peptide
  • Motilin-related Peptide
  • MTLRPgrowth hormone secretagogue receptor ligand
  • obestatin
  • Protein M46


GHRL (Ghrelin/Obestatin Prepropeptide) is a 117 aa precursor peptide that is processed into two chains, Ghrelin (aa24-51) and Obestatin (aa76-98).  The 18 kDa prepropeptide is cleaved into proGhrelin, and then further processed into mature Ghrelin by prohormone convertases.  Mature Ghrelin is modified with an N-octanoyl group on serine 3 which is required for receptor binding.  Ghrelin and Obestatin are predominantly synthesized in the gastric mucosa.  Ghrelin plays a role in growth factor release and appetite suppression as well as many other functions in a variety of organs.  Obestatin is a putative hormone that has been suggested to have opposite effects on growth factor release and appetite as Ghrelin. 


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Ghrelin Antibody (MAB8200)(5)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: ICC, IHC.

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Showing Publications 1 - 5 of 5.
Publications using MAB8200 Applications Species
XX Yu, WL Qiu, L Yang, YC Wang, MY He, D Wang, Y Zhang, LC Li, J Zhang, Y Wang, CR Xu Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans Cell Research, 2021-03-10;0(0):. 2021-03-10 [PMID: 33692492] (IHC, Mouse) IHC Mouse
L Ribeiro-Pa, AC Jarry, JB Cavin, A Willemetz, J Le Beyec, A Sannier, S Benadda, AL Pelletier, M Hourseau, T Léger, B Morlet, A Couvelard, Y Anini, S Msika, JP Marmuse, S Ledoux, M Le Gall, A Bado Bariatric surgery induces a new gastric mucosa phenotype with increased functional glucagon-like peptide-1 expressing cells Nature Communications, 2021-01-04;12(1):110. 2021-01-04 [PMID: 33397977] (IHC, Rat) IHC Rat
T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals Nat Commun, 2019-10-11;10(1):4647. 2019-10-11 [PMID: 31604927] (ICC, IHC, Human, Mouse) ICC, IHC Human, Mouse
R Azzarelli, S Rulands, S Nestorowa, J Davies, S Campinoti, S Gillotin, P Bonfanti, B Göttgens, M Huch, B Simons, A Philpott Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells Sci Rep, 2018-10-18;8(1):15374. 2018-10-18 [PMID: 30337647] (IHC, Mouse) IHC Mouse
P Rodnoi, M Rajkumar, ASM Moin, SK Georgia, AE Butler, S Dhawan Neuropeptide Y expression marks partially differentiated ? cells in mice and humans JCI Insight, 2017-06-15;2(12):. 2017-06-15 [PMID: 28614797] (IHC, Mouse) IHC Mouse

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Blogs on Ghrelin.

Ghrelin: Targeting the Hunger Hormone to Combat Obesity and Type 2 Diabetes
As the hormone ghrelin is linked to appetite and weight gain, as well as impaired glucose-induced insulin secretion, there is considerable interest in this peptide as a potential drug target. Although the overall lack of success in this field has been...  Read full blog post.

Shades of Ghrelin in Weight Homeostasis
The neuropeptide and gut hormone Ghrelin is an endogenous ligand for the growth hormone (GH)-secretagogue receptor (GHSR) within the central nervous system. This pathway has received a great deal of attention and heavy study within the last decade bec...  Read full blog post.

Appetite and Energy: A Ghrelin Balancing Act
Ghrelin is the only potent orexigenic peptide in circulation. It stimulates food intake and leads to metabolism regulation, positive energy balance, adipogenesis, and body weight gain. However, in studies using ghrelin antibodies, the physiological si...  Read full blog post.

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Gene Symbol GHRL