Human Serpin A12 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Serpin A12 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: SERPINA12

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Serpin A12 DuoSet ELISA, 15 Plate

• antitrypsin), member 12
• member 12
• OL-64
• OL-64Visceral adipose-specific serpin
• serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase
• Serpin A12
• serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
• Vaspin
• Visceral adipose tissue-derived serine protease inhibitor

Background

The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.

Publications for Serpin A12 (DY4410)(2)

Publications using DY4410

• Tarabeih, N;Kalinkovich, A;Shalata, A;Higla, O;Livshits, G; Pro-Inflammatory Biomarkers Combined with Body Composition Display a Strong Association with Knee Osteoarthritis in a Community-Based Study Biomolecules 2023-08-28 [PMID: 37759715] (Human)
• J Rueda-Goto, R López-Mejí, S Remuzgo-Ma, V Pulito-Cue, A Corrales, L Lera-Gómez, V Portilla, Í González-M, R Blanco, R Expósito, C Mata, J Llorca, V Hernández-, C Rodríguez-, N Barbarroja, RO Castro, E Vicente, C Fernández-, MP Martínez-V, D Castro-Cor, J Anino-Fern, D Peiteado, C Plasencia-, E Galíndez-A, ML García-Viv, O Gualillo, JC Quevedo-Ab, S Castañeda, I Ferraz-Ama, MÁ González-G, F Genre Vaspin in atherosclerotic disease and cardiovascular risk in axial spondyloarthritis: a genetic and serological study Arthritis Research & Therapy, 2021-04-13;23(1):111. 2021-04-13 [PMID: 33849644] (Human)

FAQs for Serpin A12 (DY4410). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: SERPINA12