Als2 Antibody (4F10) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: Als2 Antibody (4F10) [H00057679-M02] - Immunofluorescence of monoclonal antibody to Als2 on HeLa cell. [antibody concentration 40 ug/ml]

Immunocytochemistry/Immunofluorescence: Als2 Antibody (4F10) [H00057679-M02] - Analysis of monoclonal antibody to ALS2 on HeLa cell . Antibody concentration 40 ug/ml.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: 4F10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Als2 Antibody (4F10) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Als2 Antibody (4F10) - Azide and BSA Free (H00057679-M02) is a monoclonal antibody validated for use in WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: ALS2 (AAH29174, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCPLGVTLTESQAENHASTALSPSTETLDRQEEVFENTLVANDQSVATELNAVSAQITSSDAMSS
• Specificity: ALS2 - amyotrophic lateral sclerosis 2 (juvenile) (4F10)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ALS2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Als2 Antibody (4F10) - Azide and BSA Free

• ALS2CR6
• alsin
• ALSJ
• amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6
• amyotrophic lateral sclerosis 2 (juvenile)
• Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
• Amyotrophic lateral sclerosis 2 protein
• FLJ31851
• IAHSP
• KIAA1563
• MGC87187
• PLSJ

Background

The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALS2
• Entrez:
  • 57679(Human)
• Uniprot:
  • AAH29174(Human)