Hu, Mu, Rt, Bv, CaApplications:
WB, ICC/IF, IHC, IHC-P, PEP-ELISAHost:
Hu, Mu, RtApplications:
ICC/IF, IHC, IHC-PHost:
Applications: WB, ELISA, S-ELISA
Host: Mouse Monoclonal
Applications: WB, ELISA, PA, PAGE, AP
Defects in ALS2, or Alsin, are the cause of amyotrophic lateral sclerosis 2 (ALS2), juvenile primary lateral sclerosis (JPLS), and infantile-onset ascending spastic paralysis (IAHSP). ALS2 is a neurodegenerative disorder which is closely related to but clinically distinct from juvenile primary lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the motor systems comprising the upper motor neurons of the motor cortex and lower motor neurons of the brain stem and spinal cord. JPLS is a neurodegenerative disorder which is closely related to but clinically distinct from amyotrophic lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the upper motor neurons of the motor cortex while the lower neurons are unaffected. IAHSP is characterized by progressive spasticity and weakness of limbs.
|Product By Gene ID
- Amyotrophic lateral sclerosis 2 protein
- amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6
- Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
- amyotrophic lateral sclerosis 2 (juvenile)
Bioinformatics Tool for Als2
Discover related pathways, diseases and genes to Als2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related Als2 Blog Posts
Check out the latest blog posts on Als2.
Read more Als2 related blogs.
|Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f... Read more.