Als2 Products

Antibodies
Als2 Antibody
Als2 Antibody
NB100-885
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Als2 Antibody
Als2 Antibody
NBP2-14284
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Als2 Antibody (4F9)
Als2 Antibody (4F9)
H00057679-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Als2 Overexpression Lysate (D ...
Als2 Overexpression Lysate (Denatu...
H00057679-T01
Species: Hu
Applications: WB
Als2 Overexpression Lysate (N ...
Als2 Overexpression Lysate (Native)
L013T6
Species: Hu
Applications: WB, IP
Proteins
Als2 Partial Recombinant Prot ...
Als2 Partial Recombinant Protein
H00057679-Q01
Species: Hu
Applications: WB, ELISA, PA
Als2 Recombinant Protein Anti ...
Als2 Recombinant Protein Antigen
NBP2-14284PEP
Species: Hu
Applications: AC
RNAi
Als2 RNAi
Als2 RNAi
H00057679-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Defects in ALS2, or Alsin, are the cause of amyotrophic lateral sclerosis 2 (ALS2), juvenile primary lateral sclerosis (JPLS), and infantile-onset ascending spastic paralysis (IAHSP). ALS2 is a neurodegenerative disorder which is closely related to but clinically distinct from juvenile primary lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the motor systems comprising the upper motor neurons of the motor cortex and lower motor neurons of the brain stem and spinal cord. JPLS is a neurodegenerative disorder which is closely related to but clinically distinct from amyotrophic lateral sclerosis. It is a progressive paralytic disorder which results from dysfunction of the upper motor neurons of the motor cortex while the lower neurons are unaffected. IAHSP is characterized by progressive spasticity and weakness of limbs.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 57679
Alternate Names
  • alsin
  • IAHSP
  • ALSJ
  • KIAA1563
  • MGC87187
  • ALS2CR6
  • FLJ31851
  • Amyotrophic lateral sclerosis 2 protein
  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 6
  • Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein
  • PLSJ
  • amyotrophic lateral sclerosis 2 (juvenile)

PTMs for Als2

Learn more about PTMs related to Als2.

Phosphorylation
Cleavage
Methylation
Glycosylation
Dephosphorylation

Bioinformatics Tool for Als2

Discover related pathways, diseases and genes to Als2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Als2 Blog Posts

Check out the latest blog posts on Als2.
Amyotrophic Lateral Sclerosis Infographic
Amyotrophic lateral sclerosis is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body. The progressive degeneration of neurons causes weakened muscles and can lead to paralysis. There is no cure f...    Read more.
Read more Als2 related blogs.