Adiponectin/Acrp30 Antibody (166126)

• Reactivity: Hu
• Applications: ELISA(Cap)
• Clone: 166126
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Adiponectin/Acrp30 Antibody (166126) Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Adiponectin
  Glu19-Asn244
  Accession # Q15848
• Specificity: Detects an epitope in the globular domain (aa 104 - 244) of human Adiponectin. In ELISAs, this antibody shows no cross-reactivity or interference with recombinant mouse (rm) Adiponectin or rh6Ckine.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: ADIPOQ
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.5-2.0 ug/mL
  • ELISA Standard (Matched Pair)
• Application Notes: ELISA Capture: Human Adiponectin/Acrp30 Antibody (Catalog # MAB10651)
  ELISA Detection: Human Adiponectin/Acrp30 Biotinylated Antibody (Catalog # BAM1065)
  Standard: Recombinant Human Adiponectin/Acrp30 (Catalog # 1065-AP)

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A or G purified from hybridoma culture supernatant
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Adiponectin/Acrp30 Antibody (166126)

• ACDC
• Acrp30
• ACRP30ADPN
• adipocyte, C1Q and collagen domain containing
• Adiponectin
• adiponectin, C1Q and collagen domain containing
• AdipoQ
• ADIPQTL1
• ApM1
• apM-1
• APM1APM-1
• C1q and collagen domain-containing protein
• GBP28
• GBP28apM1
• Gelatin-binding protein

Background

Adiponectin, also known as Adipocyte Complement-Related Protein of 30 kDa (Acrp30), is secreted from adipocytes and has been implicated in energy homeostasis and obesity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Adiponectin/Acrp30 Antibody (MAB10651)(4)

Publications using MAB10651

• R Giacconi, M Malavolta, A Bürkle, M Moreno-Vil, C Franceschi, M Capri, PE Slagboom, EHJM Jansen, MET Dollé, T Grune, D Weber, A Hervonen, W Stuetz, N Breusing, F Ciccarone, M Zampieri, V Aversano, P Caiafa, L Formentini, F Piacenza, E Pierpaoli, A Basso, M Provincial, M Cardelli Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians Nutrients, 2019;11(12):. 2019 [PMID: 31817660] (ELISA Capture, Human)
• Schipper HS, De Jager W, van Dijk ME, Meerding J, Zelissen PM, Adan RA, Prakken BJ, Kalkhoven E A multiplex immunoassay for human adipokine profiling. Clin. Chem., 2010;56(0):1320. 2010 [PMID: 20530731] (Luminex Development, Human)
• Hu H, Kwun J, Aizenstein BD, Knechtle SJ Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 2009;87(12):1814-20. 2009 [PMID: 19543058] (Antibody Array Development, Human)
• Majuri A, Santaniemi M, Rautio K, Kunnari A, Vartiainen J, Ruokonen A, Kesaniemi YA, Tapanainen JS, Ukkola O, Morin-Papunen L Rosiglitazone treatment increases plasma levels of adiponectin and decreases levels of resistin in overweight women with PCOS: a randomized placebo-controlled study. Eur. J. Endocrinol., 2007;156(2):263-9. 2007 [PMID: 17287417] (ELISA Development, Human)

Bioinformatics

• Gene Symbol: ADIPOQ
• Uniprot:
  • Q15848()