ABCE1 Antibody


Western Blot: ABCE1 Antibody [NB400-116] - WB analysis of ABCE1 in A431 lysate.
Immunocytochemistry/ Immunofluorescence: ABCE1 Antibody [NB400-116] - ABCE1 antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Product Details

Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IP
0.2 mg/ml

ABCE1 Antibody Summary

A fusion protein containing amino acids 1-119 of human ABCE1 [UniProt# P61221]
Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
Immunogen affinity purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.05% Sodium Azide
0.2 mg/ml
Immunogen affinity purified


  • Western Blot 1:250-1:1000
  • Immunocytochemistry/Immunofluorescence 1:40
  • Immunoprecipitation 1:1000
Application Notes
This ABCE1 antibody is useful for Immunoprecipitaton, Immunocytochemistry/Immunofluorescence, and Western Blot. In ICC/IF, mitochondrial staining was observed in HeLa cells. In Western Blot, a band was seen ~68 kD representing ABCE1.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
68 kDa
Read Publications using
NB400-116 in the following applications:

Reactivity Notes


Alternate Names for ABCE1 Antibody

  • 2'-5'-oligoadenylate-binding protein
  • ATP-binding cassette, sub-family E (OABP), member 1
  • huHP68
  • OABP
  • Ribonuclease 4 inhibitor
  • ribonuclease L (2'-5'-oligoisoadenylate synthetase-dependent) inhibitor
  • RLIABC38
  • RNase L inhibitor
  • RNASELIRNS4IATP-binding cassette sub-family E member 1


ABCE1 (ATP-binding cassette sub-family E member 1), also named RLI or HP68, belongs to ABC transporter superfamily/ABCE family and is composed of two nucleotide binding domains and an N-terminal Fe-S binding domain. ABCE1 heterodimerizes with RNASEL leading to its inhibition and has the ability to associates with HIV-1 Vif, HIV-1, HIV-2 and SIV Gag proteins. Evolutionarily highly conserved, ABCE1 localize to cytoplasm/mitochondrion as well as to virus formation clusters at plasma membrane and its highest expression has been observed in brain, kidney, prostate etc. where it gets activated by HIV-1 or EMCV (encephalomyocarditis virus). Originally identified as an RNase L inhibitor, ABCE1 has now been implicated in more fundamental processes of translation and ribosome biogenesis, and can regulate functions including viral infection/assembly of immature HIV-1 capsids, tumor cell proliferation, anti-apoptosis and is also a candidate for tumor-suppressor protein.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ABCE1 Antibody (NB400-116)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for ABCE1 Antibody (NB400-116). (Showing 1 - 1 of 1 FAQs).

  1. Could you please provide me with Immunprecipitation protocol specific for ABCE1 Antibody (NB400-116)?
    • We do not have a product specific Immunoprecipitation protocol for this product, however we do have a general IP protocol.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB400-116AF405
Alexa Fluor (R) 488 Labeled NB400-116AF488
Alexa Fluor (R) 647 Labeled NB400-116AF647
Alexa Fluor (R) 700 Labeled NB400-116AF700
Biotin Labeled NB400-116B
DyLight 405 Labeled NB400-116V
DyLight 488 Labeled NB400-116G
DyLight 550 Labeled NB400-116R
DyLight 650 Labeled NB400-116C
FITC Labeled NB400-116F
HRP Labeled NB400-116H

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Contact Information

Product PDFs


Gene Symbol ABCE1

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