MRP1 Antibody (IU2H10)


Western Blot: MRP1 Antibody (IU2H10) [NB400-156] - Vector-transfected HEK293 cells 2: MRP1-transfected cells, prep1 3: MRP1-transfected cells, prep2 (the lower band is a degradation product.
Immunocytochemistry/ Immunofluorescence: MRP1 Antibody (IU2H10) [NB400-156] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IP
1.0 mg/ml

MRP1 Antibody (IU2H10) Summary

Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].
Amino acids 8-17 of human MRP1.
Protein G purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1.0 mg/ml
Protein G purified


  • Western Blot 1:500
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunoprecipitation
Application Notes
This MRP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot. In Western blot a band was observed at ~170-190 kDa in transfected samples. There may be a lower MW band that is a degredation product. Flow Cytometry, Immunoprecipitation and ELISA were reported in scientific literature.
Read Publications using
NB400-156 in the following applications:

  • 1 publication
  • 2 publications
  • 2 publications
  • IP
    1 publication
  • WB
    3 publications

Alternate Names for MRP1 Antibody (IU2H10)

  • ABC29
  • ABCC
  • ABCC1
  • ATP-binding cassette sub-family C member 1
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • EC 3.6.3
  • EC
  • GS-X
  • Leukotriene C(4) transporter
  • LTC4 transporter
  • MRP1DKFZp781G125
  • MRPDKFZp686N04233
  • multidrug resistance associated protein 1
  • multidrug resistance protein
  • multidrug resistance-associated protein 1
  • multiple drug resistance protein 1
  • multiple drug resistance-associated protein


The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, B/N, ICC/IF, IHC, IHC-P, IP
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: WB, ELISA, IHC, IHC-P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, PEP-ELISA
Species: Hu, Mu
Applications: WB
Species: Hu
Applications: WB, IHC
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow, IHC, IHC-Fr
Species: Hu, Mu, Ca
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu, Rt
Applications: WB, ELISA, Flow, ICC/IF, IP

Publications for MRP1 Antibody (NB400-156)(9)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 5 applications: ELISA, FLOW, ICC/IF, IP, WB.

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Showing Publications 1 - 9 of 9.
Publications using NB400-156 Applications Species
Koshkin V, Ailles LE, Liu G, Krylov SN. Metabolic suppression of a drug resistant subpopulation in cancer spheroid cells J. Cell. Biochem. 2015 Jun 06 [PMID:26054050] (FLOW, Human) FLOW Human
Grybauskas A, Koga T, Kuprys PV et al. ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells. Mol. Vis. 2015 Mar 24 [PMID:25802484] (WB, Human, Mouse, Rat) WB Human, Mouse, Rat
Kurihara Y, Sawazumi T, Takeuchi T. Exploration of interactions between membrane proteins embedded in supported lipid bilayers and their antibodies by reflectometric interference spectroscopy-based sensing. Analyst. 2014 Oct 15 [PMID:25270526] (Human) Human
Chen YY, Lukka PB, Joseph WR et al. Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. Cancer Chemother. Pharmacol. 2014 May 07 [PMID:24801172] (ICC/IF, Mouse) ICC/IF Mouse
Tiwari AK, Zhang R, Gallo JM et al. Overlapping functions of ABC transporters in topotecan disposition as determined in gene knockout Mouse models. Mol Cancer Ther 2013 May 1 [PMID:23635651] (WB, Mouse) WB Mouse
Chen Q, Yang Y, Li L, Zhang JT. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem;281(41):31152-63. 2006 Oct 13. [PMID:16914551]
Binyamin L, Assaraf YG, Reiter Y. Probing ATP-dependent conformational changes in the multidrug resistance protein 1 (MRP1/ABCC1) in live tumor cells with a novel recombinant single-chain Fv antibody targeted to the extracellular N-terminus. Int J Cancer;116(5):703-9. 2005 Sep 20. [PMID:15838832]
Yang Y, Chen Q, Zhang JT. Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. J Biol Chem;277(46):44268-77. 2002 Nov 15. [PMID:12235150] (FLOW, Human) FLOW Human
Chen Q, Yang Y, Liu Y, Han B, Zhang JT. Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1. Biochemistry;41(29):9052-62. 2002 Jul 23. [PMID:12119019] (WB, ELISA, IP, ICC/IF, Human) WB, ELISA, IP, ICC/IF Human

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB400-156AF405
Alexa Fluor (R) 488 Labeled NB400-156AF488
Alexa Fluor (R) 647 Labeled NB400-156AF647
Alexa Fluor (R) 700 Labeled NB400-156AF700
Allophycocyanin Labeled NB400-156APC
Biotin Labeled NB400-156B
DyLight 350 Labeled NB400-156UV
DyLight 405 Labeled NB400-156V
DyLight 405LS Labeled NB400-156V3
DyLight 488 Labeled NB400-156G
DyLight 550 Labeled NB400-156R
DyLight 650 Labeled NB400-156C
DyLight 680 Labeled NB400-156FR
DyLight 755 Labeled NB400-156IR
FITC Labeled NB400-156F
HRP Labeled NB400-156H
PE Labeled NB400-156PE
PerCP Labeled NB400-156PCP

Additional MRP1 Antibody (IU2H10) Products

MRP1 NB400-156

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Blogs on MRP1.

ABC Membrane transporters and the role of MRP1 in drug resistance
ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes.  Multidrug resistance-associated protein 1 (MRP1) is a member o...  Read full blog post.

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Product PDFs


Gene Symbol ABCC1

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