Orthogonal Strategies: Dual RNAscope ISH-IHC: MRP1 Antibody (IU2H10) [NB400-156] - Formalin-fixed paraffin-embedded tissue sections of human testis were probed for MRP1 mRNA (ACD RNAScope Probe, catalog # 435591; ...read more
Immunocytochemistry/ Immunofluorescence: MRP1 Antibody (IU2H10) [NB400-156] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained ...read more
Western Blot: MRP1 Antibody (IU2H10) [NB400-156] - Vector-transfected HEK293 cells 2: MRP1-transfected cells, prep1 3: MRP1-transfected cells, prep2 (the lower band is a degradation product.)
This MRP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot. In Western blot a band was observed at ~170-190 kDa in transfected samples. There may be a lower MW band that is a degradation product. Flow Cytometry, Immunoprecipitation and ELISA were reported in scientific literature. This antibody is CyTOF ready.
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Protein G purified
Alternate Names for MRP1 Antibody (IU2H10)
ATP-binding cassette sub-family C member 1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Leukotriene C(4) transporter
multidrug resistance associated protein 1
multidrug resistance protein
multidrug resistance-associated protein 1
multiple drug resistance protein 1
multiple drug resistance-associated protein
The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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