YME1L1 Antibody (OTI2G10)

Western Blot: YME1L1 Antibody (2G10) [NBP2-46382] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY YME1L1.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI2G10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

YME1L1 Antibody (OTI2G10) Summary

• Description: Novus Biologicals Mouse YME1L1 Antibody (OTI2G10) (NBP2-46382) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 26-345 of human YME1L1(NP_647474) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: YME1L1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Theoretical MW: 83.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for YME1L1 Antibody (OTI2G10)

• ATP-dependent metalloprotease FtsH1 homolog
• ATP-dependent metalloprotease FtsH1
• ATP-dependent metalloprotease YME1L1
• EC 3.4.24
• EC 3.4.24.-
• FTSH
• FTSH1
• MEG4
• Meg-4
• PAMPATP-dependent zinc metalloprotease YME1L1
• Presenilin-associated metalloprotease
• YME1 (S.cerevisiae)-like 1
• YME1-like 1 (S. cerevisiae)
• YME1-like protein 1
• YME1Lmeg-4

Background

The protein encoded by the YME1L1 gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: YME1L1