YME1L1 Antibody (OTI2G10) [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI2G10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

YME1L1 Antibody (OTI2G10) [Alexa Fluor® 488] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 26-345 of human YME1L1 (NP_647474) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: YME1L1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for YME1L1 Antibody (OTI2G10) [Alexa Fluor® 488]

• ATP-dependent metalloprotease FtsH1 homolog
• ATP-dependent metalloprotease FtsH1
• ATP-dependent metalloprotease YME1L1
• EC 3.4.24
• EC 3.4.24.-
• FTSH
• FTSH1
• MEG4
• Meg-4
• PAMPATP-dependent zinc metalloprotease YME1L1
• Presenilin-associated metalloprotease
• YME1 (S.cerevisiae)-like 1
• YME1-like 1 (S. cerevisiae)
• YME1-like protein 1
• YME1Lmeg-4

Background

The protein encoded by the YME1L1 gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: YME1L1