Serpin B6 Antibody (OTI1C5)

Images

 
Western Blot: Serpin B6 Antibody (1C5) [NBP2-01650] - Analysis of extracts (10ug) from 9 Human tissue by using anti-SERPINB6 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; ...read more
Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Human liver tissue using anti-SerpinB6 mouse monoclonal antibody.
Flow Cytometry: SerpinB6 Antibody (1C5) [NBP2-01650] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SerpinB6 antibody, and then ...read more
Western Blot: SerpinB6 Antibody (1C5) [NBP2-01650] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SerpinB6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell ...read more
Western Blot: SerpinB6 Antibody (1C5) [NBP2-01650] Analysis of extracts (35ug) from 9 different cell lines by using anti-SerpinB6 monoclonal antibody.
Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SerpinB6 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SerpinB6 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SerpinB6 mouse monoclonal antibody.
Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Human endometrium tissue using anti-SerpinB6 mouse monoclonal antibody.
Flow Cytometry: SerpinB6 Antibody (1C5) [NBP2-01650] - Analysis of Jurkat cells, using anti-SerpinB6 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Reactivity Hu, Mu, PmSpecies Glossary
Applications WB, Flow, IHC, IHC-P
Clone
OTI1C5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.71 mg/ml

Order Details

Serpin B6 Antibody (OTI1C5) Summary

Immunogen
Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SERPINB6
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-2000
  • Flow Cytometry 1:100
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
Publications
Read Publication using NBP2-01650.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
0.71 mg/ml
Purity
Affinity purified

Alternate Names for Serpin B6 Antibody (OTI1C5)

  • CAP
  • CAPMGC111370
  • Cytoplasmic antiproteinase
  • deafness, autosomal recessive 91
  • DFNB91
  • Peptidase inhibitor 6
  • PI6
  • PI-6
  • PI6MSTP057
  • Placental thrombin inhibitor
  • protease inhibitor 6 (placental thrombin inhibitor)
  • PTI
  • PTIDKFZp686I04222
  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6
  • Serpin B6
  • serpin peptidase inhibitor, clade B (ovalbumin), member 6
  • SPI3

Background

The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Serpin B6 Antibody (NBP2-01650)(1)


Showing Publication 1 - 1 of 1.
Publication using NBP2-01650 Applications Species
Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-74111AF350
Alexa Fluor 405 NBP2-74111AF405
Alexa Fluor 488 NBP2-74111AF488
Alexa Fluor 532 NBP2-74111AF532
Alexa Fluor 594 NBP2-74111AF594
Alexa Fluor 647 NBP2-74111AF647
Alexa Fluor 700 NBP2-74111AF700
Alexa Fluor 750 NBP2-74111AF750
Allophycocyanin NBP2-74111APC
Biotin NBP2-74111B
DyLight 350 NBP2-74111UV
DyLight 405 NBP2-74111V
DyLight 488 NBP2-74111G
DyLight 550 NBP2-74111R
DyLight 594 NBP2-74111DL594
DyLight 650 NBP2-74111C
DyLight 680 NBP2-74111FR
DyLight 755 NBP2-74111IR
FITC NBP2-74111F
HRP NBP2-74111H
Janelia Fluor 549 NBP2-74111JF549
Janelia Fluor 646 NBP2-74111JF646
PE NBP2-74111PE
PerCP NBP2-74111PCP

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Bioinformatics

Gene Symbol SERPINB6
Entrez