XRCC1 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, Mycoplasma
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 500 SE

XRCC1 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 600 and the C-terminus (residue 633) of human X-ray Repair Cross Complementing protein 1 using the numbering given in entry NP_006288.1 (GeneID 7515).
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: XRCC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Knockdown Validated
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for XRCC1 Antibody [mFluor Violet 500 SE]

• DNA repair protein XRCC1
• RCC
• X-ray repair complementing defective repair in Chinese hamster cells 1
• X-ray repair cross-complementing protein 1
• X-ray-repair, complementing defective, repair in Chinese hamster

Background

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA Ligase III-a.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: XRCC1