VHLL Antibody - Azide and BSA Free

Western Blot: VHLL Antibody [H00391104-B01P-50ug] - Analysis of VHLL expression in transfected 293T cell line by VHLL MaxPab polyclonal antibody. Lane 1: VHLL transfected lysate(15.3 KDa). Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

VHLL Antibody - Azide and BSA Free Summary

• Immunogen: VHLL (ADR83480.1, 1 a.a. - 139 a.a.) full-length human protein. MPWRAGNGVGLEAQAGTQEAGPEEYCQEELGAEEEMAARAAWPVLRSVNSRELSRIIICNHSPRIVLPVWLNYYGKLLPYLTLLPGRDFRIHNFRSHPWLFRDARTHDKLLVNQTELFVPSSNVNGQPVFANITLQCIP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: VHLL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for VHLL Antibody - Azide and BSA Free

• VHL-like protein
• VHLP
• VLPVHL pseudogene
• von Hippel-Lindau tumor suppressor-like
• von Hippel-Lindau-like protein

Background

Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that the selectivelyubiquitinates the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediateddegradation. Inactivation of VHL causes VHL disease and sporadic kidney cancer. This gene encodes a VHL homolog thatlacks one of two key domains necessary for VHL function. It binds HIF alpha but fails to recruit the E3 ubiquitinligase complex, and therefore functions as a dominant-negative VHL and a protector of HIF alpha. This gene isintronless and predominantly expressed in the placenta, and may contribute to the regulation of oxygen homeostasis andneovascularization during placenta development. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VHLL
• Entrez:
  • 391104(Human)
• Uniprot:
  • ADR83480.1(Human)