VEGFR1/Flt-1 Antibody

Images

 
Western Blot: VEGF R1/Flt-1 Antibody [NBP1-18631] - The polyclonal antibody was raised against the unique C-terminal end of the native human soluble Flt-1 (amino acids: CNKKAVFSRISKFKSTRNDSTTQSNVKH). The Protein-A ...read more
Immunocytochemistry/ Immunofluorescence: VEGF R1/Flt-1 Antibody [NBP1-18631] - Staining (green) using our polyclonal antibody directed against the C-terminal end of native soluble VEGFR-1/Flt-1 (left panel) and our ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

VEGFR1/Flt-1 Antibody Summary

Immunogen
This antibody was raised against the following peptide sequence from Isoform 2 of the human VEGFR1 protein (P17948): GEHCNKKAVFSRISKFKSTRNDCTTQSNVKH.
Marker
Endothelial Cell Marker
Specificity
soluble VEGFR-1/Flt-1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FLT1
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1-5 ug
  • ELISA 2.5 ug/ml
  • Immunocytochemistry/Immunofluorescence 1-5 ug
  • Immunoprecipitation 1-5 ug/ml
Application Notes
Western Blot: The antibody can be used at 0.5 - 2 ug/ml to detect native human sVEGFR-1/Flt-1.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with 0.2 ml distilled water.

Alternate Names for VEGFR1/Flt-1 Antibody

  • EC 2.7.10
  • EC 2.7.10.1
  • FLT
  • FLT1
  • Flt-1
  • Fms-like tyrosine kinase 1
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor)
  • FRT
  • Tyrosine-protein kinase FRT
  • Tyrosine-protein kinase receptor FLT
  • vascular endothelial growth factor receptor 1
  • Vascular permeability factor receptor
  • VEGF R1
  • VEGFR1
  • VEGFR-1

Background

VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional VEGFR1/Flt-1 Products

Bioinformatics Tool for VEGFR1/Flt-1 Antibody (NBP1-18631)

Discover related pathways, diseases and genes to VEGFR1/Flt-1 Antibody (NBP1-18631). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for VEGFR1/Flt-1 Antibody (NBP1-18631)

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Bioinformatics

Gene Symbol FLT1
Entrez