VEGF 165 Antibody (Bevacizumab) - Chimeric - Azide and BSA Free

• Reactivity: Hu
• Applications: WB, ELISA, Flow, IP, B/N
• Clone: Bevacizumab
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

VEGF 165 Antibody (Bevacizumab) - Chimeric - Azide and BSA Free Summary

• Description: Novus Biologicals Rabbit VEGF 165 Antibody (Bevacizumab) - Chimeric - Azide and BSA Free (NBP2-59638) is a recombinant monoclonal antibody validated for use in WB, ELISA, Flow and IP. Anti-VEGF 165 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant human VEGF
• Specificity: This antibody binds native and reduced human VEGF (isoform 165).
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: VEGFA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • ELISA
  • Flow Cytometry
  • Immunoprecipitation
  • Western Blot
• Application Notes: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Packaging, Storage & Formulations

• Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
• Buffer: PBS
• Preservative: 0.02% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for VEGF 165 Antibody (Bevacizumab) - Chimeric - Azide and BSA Free

• biosimilar antibody
• biosimilars
• MVCD1
• vascular endothelial growth factor A
• Vascular permeability factor
• VEGF-A
• VEGFMGC70609
• VPFvascular endothelial growth factor

Background

VEGF (Vascular endothelial growth factor) is the only growth factor that stimulates vascular permeability. It promotes endothelial proliferation and survival, angiogenesis, vasculognesis and inhibits apoptosis. VEGF mitogenic activity is specific for endothelial cell and that makes it distinct among other growth factors. VEGF is thought to be important in the pathophysiology of neuronal and other tumors, by functioning as a promter of angiogenesis for human gliomas. Human VEGF occurs in several molecular variants and the 165 form is the most common form in most tissues. Biological activities of VEGF are not species-specific and glycosylation is not required for biological activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VEGF 165 Antibody (NBP2-59638)(1)

Publication using NBP2-59638

• Hajal C, Offeddu GS, Shin Y Et al. Engineered human blood-brain barrier microfluidic model for vascular permeability analyses Nat Protoc 2022-01-08 [PMID: 34997242]
  
  Details:
  Citation using the Alexa Fluor 647 version of this antibody.

Bioinformatics

• Gene Symbol: VEGFA