This antibody was developed against Recombinant Protein corresponding to amino acids: QPLVGIETLPPDLRDFVEEDNQRFEKELEEWDAQLAQKALQEKLLASQKLRESETSVTTAQAAGDPEYLEQPSRSDFSKHLKEETIQIITKASHEHEDKSPETVLQSIMMTPNMQGIIMAIGKSRSVYDRCGPEAGFFK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
USP25
Purity
Immunogen affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for USP25 Antibody - BSA Free
Deubiquitinating enzyme 25
EC 3.1.2.15
EC 3.4.19.12
ubiquitin carboxyl-terminal hydrolase 25
ubiquitin specific peptidase 25
ubiquitin specific protease USP2510USP21ubiquitin specific protease 25
ubiquitin thioesterase 25
Ubiquitin Thiolesterase 25
ubiquitin-specific processing protease 25
Ubiquitin-specific-processing protease 25
USP on chromosome 21
USP25
Background
USP25 is a ubiquitin-specific protease. Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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