UCP3 Antibody

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Western Blot: UCP3 Antibody [NBP2-24608] - Analysis of UCP3 in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart

Product Details

Summary
Reactivity Hu, Mu, Rt, Pm, Po, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

UCP3 Antibody Summary

Immunogen
A portion of amino acids 125-175 of human UCP3 was used as the immunogen.
Predicted Species
Porcine (94%), Canine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
UCP3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-2.0 ug/ml
Publications
Read Publications using
NBP2-24608 in the following applications:

  • WB
    1 publication

Reactivity Notes

The amino acid sequence used as immunogen is 84% homologous in bovine.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for UCP3 Antibody

  • mitochondrial uncoupling protein 3
  • SLC25A9Solute carrier family 25 member 9
  • UCP 3
  • uncoupling protein 3 (mitochondrial, proton carrier)
  • Uncoupling protein-3

Background

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP 1 is abundantly expressed in brown adipose tissue of mammals. UCP 1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP 2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP 2 to be expressed by a variety of tissues. UCP 3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-24608
Species: Hu, Mu, Rt, Pm, Po, Ca
Applications: WB
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Publications for UCP3 Antibody (NBP2-24608)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: WB.


Filter By Application
WB
(1)
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Mouse
(1)
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Showing Publications 1 - 2 of 2.
Publications using NBP2-24608 Applications Species
Rupert JE, Narasimhan A, Jengelley DHA et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia The Journal of experimental medicine Jun 7 2021 [PMID: 33851955] (WB, Mouse) WB Mouse
Sekerci G Sicanlara meteorin-like protein uygulamasının hipotalamus-hipofiz-tiroid aksı ve periferal uncoupling proteinler Uzerindeki etkileri Thesis Jul 13 1905

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol UCP3
Uniprot