32 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NBP1-76695 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Protein A purified
Alternate Names for TWEAK/TNFSF12 Antibody
TNF-related weak inducer of apoptosis
tumor necrosis factor (ligand) superfamily, member 12
tumor necrosis factor ligand superfamily member 12
TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains. Despite its predicted molecular weight of 27kDa, TWEAK may migrate at aberrant positions in SDS-PAGE.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for TWEAK/TNFSF12 Antibody (NBP1-76695). (Showing 1 - 1 of 1 FAQs).
We recently purchased a TWEAK antibody (NBP1-76695) from you to use in Western blot. I notice that it has an ELISA application; can we biotinylate this antibody to use it as a detection agent in ELISA or can you suggest an appropriate detection antibody?
This antibody can certainly be conjugated directly to biotin. We have Lightning-Link kits that can do this for you because of the buffer and purification of this one. As far as detection antibodies are concerned, you could use a secondary against Rabbit IgG conjugated to biotin as your detection if that is what you would prefer to do.
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