Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit Summary

• Background: The Quantikine Human BAFF/BLyS Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human BAFF/BLyS in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human BAFF/BLyS and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human BAFF/BLyS showed linear curves that were parallel to the standard curves obta...ined using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human BAFF.
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• Specificity: Natural and recombinant human BAFF/BLyS
• Source: N/A
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: TNFSF13B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Interference observed with 1 or more available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human BAFF/BLyS/TNFSF13B Quantikine ELISA Kit

• ApoL related ligand TALL-1
• B lymphocyte stimulator
• BAFF
• BAFFB-cell activating factor
• B-cell-activating factor
• BLyS
• BLYSB-lymphocyte stimulator
• CD257 antigen
• CD257
• Dendritic cell-derived TNF-like molecule
• DTL
• TALL1
• TALL-1delta BAFF
• TALL1Delta4 BAFF
• THANK
• TNF- and APOL-related leukocyte expressed ligand 1
• TNF and ApoL-related leukocyte expressed ligand 1
• TNF homolog that activates apoptosis
• TNFSF13B
• TNFSF20
• tumor necrosis factor (ligand) superfamily, member 13b
• tumor necrosis factor (ligand) superfamily, member 20
• tumor necrosis factor ligand superfamily member 13B
• tumor necrosis factor superfamily, member 13b
• tumor necrosis factor-like protein ZTNF4
• ZTNF4

Background

BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for BAFF/BLyS/TNFSF13B (DBLYS0B)(69)

Publications using DBLYS0B

• Morali, K;Steuten, J;Russo, F;Romana Santoni de Sio, F;Menage, C;Consoli, V;Annoni, A;Iaia, S;van Ham, SM;Ten Brinke, A;Gregori, S; Antigen-specific B cell response regulation by IL-10-producing tolerogenic dendritic cells Science advances 2025-11-21 [PMID: 41270166] (Human)
• Lin, J;Deng, W;Liao, J;Ke, D;Cui, L;Zhong, H;Huang, K;Jiang, L;Chen, Q;Xu, F;Tang, F; BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-?B-I?B? signaling International immunopharmacology 2023-12-01 [PMID: 38041956] (Human)
• Rahmé, Z;Franco, C;Cruciani, C;Pettorossi, F;Zaramella, A;Realdon, S;Iaccarino, L;Frontini, G;Moroni, G;Doria, A;Ghirardello, A;Gatto, M; Characterization of Serum Cytokine Profiles of Patients with Active Lupus Nephritis International journal of molecular sciences 2023-10-04 [PMID: 37834330] (Human)
• Gyllemark, P;Sjöwall, J;Forsberg, P;Ernerudh, J;Henningsson, AJ; Intrathecal Th17-driven inflammation is associated with prolonged post-treatment convalescence for patients with Lyme neuroborreliosis Scientific reports 2023-06-15 [PMID: 37322136] (Human)
• R Lievin, H Hendel-Cha, A Baldé, R Lancar, M Algarte-Gé, R Krzysiek, D Costagliol, L Assoumou, Y Taoufik, C Besson Increased Production of B-Cell Activating Cytokines and Altered Peripheral B-Cell Subset Distribution during HIV-Related Classical Hodgkin Lymphoma Cancers, 2021-12-28;14(1):. 2021-12-28 [PMID: 35008292] (Human)
• W Alturaiki, A Mubarak, SA Mir, A Afridi, M Premanatha, S Mickymaray, R Vijayakuma, SA Alsagaby, SG Almalki, F Alghofaili, AK Alnemare, BF Flanagan Plasma levels of BAFF and APRIL are elevated in patients with asthma in Saudi Arabia Saudi journal of biological sciences, 2021-08-23;28(12):7455-7459. 2021-08-23 [PMID: 34867050] (Human)
• X Wang, J Huang, A Zhang, C Fang, Q Ma, P Jiang Altered expression profile of BAFF receptors on peripheral blood B lymphocytes in Graves' disease BMC endocrine disorders, 2021-04-29;21(1):88. 2021-04-29 [PMID: 33926416] (Human)
• S Sendic, L Mansouri, S Lundberg, A Nopp, SH Jacobson, J Lundahl B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy PLoS ONE, 2021-03-19;16(3):e0248056. 2021-03-19 [PMID: 33740017] (Human)
• RLI Crake, MR Strother, E Phillips, MP Doogue, M Zhang, CMA Frampton, BA Robinson, MJ Currie Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study Scientific Reports, 2021-03-11;11(1):5648. 2021-03-11 [PMID: 33707475] (Human)
• C Rönnberg, A Lugaajju, A Nyman, U Hammar, M Bottai, MJ Lautenbach, C Sundling, F Kironde, KEM Persson A longitudinal study of plasma BAFF levels in mothers and their infants in Uganda, and correlations with subsets of B cells PLoS ONE, 2021-01-19;16(1):e0245431. 2021-01-19 [PMID: 33465125] (Human)
• T Robinson, A Abdelhak, T Bose, E Meinl, M Otto, UK Zettl, R Dersch, H Tumani, S Rauer, A Huss Cerebrospinal Fluid Biomarkers in Relation to MRZ Reaction Status in Primary Progressive Multiple Sclerosis Cells, 2020-11-25;9(12):. 2020-11-25 [PMID: 33255854] (Human)
• M Barman, H Rabe, B Hesselmar, S Johansen, AS Sandberg, AE Wold Cord Blood Levels of EPA, a Marker of Fish Intake, Correlate with Infants' T- and B-Lymphocyte Phenotypes and Risk for Allergic Disease Nutrients, 2020-09-30;12(10):. 2020-09-30 [PMID: 33007868] (Human)
• Z Liba, M Vaskova, J Zamecnik, J Kayserova, H Nohejlova, M Ebel, J Sanda, GA Ramos-Rive, K Brozova, P Liby, M Tichy, P Krsek An immunotherapy effect analysis in Rasmussen encephalitis BMC neurology, 2020-09-24;20(1):359. 2020-09-24 [PMID: 32972372] (Human)
• DM Muema, NA Akilimali, OC Ndumnego, SS Rasehlo, R Durgiah, DBA Ojwach, N Ismail, M Dong, A Moodley, KL Dong, ZM Ndhlovu, JM Mabuka, BD Walker, JK Mann, T Ndung'u Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection BMC Med, 2020-03-25;18(1):81. 2020-03-25 [PMID: 32209092] (Human)
• G Piuri, K Basello, G Rossi, CM Soldavini, S Duiella, G Privitera, A Spadafranc, A Costanzi, E Tognon, M Cappellett, PA Corsetto, AM Rizzo, AF Speciani, E Ferrazzi Methylglyoxal, Glycated Albumin, PAF, and TNF-&alpha: Possible Inflammatory and Metabolic Biomarkers for Management of Gestational Diabetes Nutrients, 2020-02-14;12(2):. 2020-02-14 [PMID: 32074941] (Human)
• J Irure-Vent, D San Segund, E Rodrigo, D Merino, L Belmar-Veg, JC Ruiz San M, R Valero, A Benito, M López-Hoyo High Pretransplant BAFF Levels and B-cell Subset Polarized towards a Memory Phenotype as Predictive Biomarkers for Antibody-Mediated Rejection Int J Mol Sci, 2020-01-25;21(3):. 2020-01-25 [PMID: 31991734] (Human)
• A Brinkhoff, Y Zeng, A Sieberichs, S Dolff, X Shilei, M Sun, H Engler, S Benson, J Korth, M Schedlowsk, A Kribben, O Witzke, B Wilde B cell dynamics during experimental endotoxemia in humans Biosci. Rep., 2019-05-17;0(0):. 2019-05-17 [PMID: 30962268] (Human)
• V Lagou, JE Garcia-Per, I Smets, L Van Horebe, M Vandebergh, L Chen, K Mallants, T Prezzemolo, K Hilven, S Humblet-Ba, M Moisse, P Van Damme, G Boeckxstae, P Bowness, B Dubois, J Dooley, A Liston, A Goris Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators Cell Rep, 2018-10-16;25(3):798-810.e6. 2018-10-16 [PMID: 30332657] (Human)
• AS Wilhelmson, M Lantero Ro, A Stubelius, P Fogelstran, I Johansson, MB Buechler, S Lianoglou, VN Kapoor, ME Johansson, JB Fagman, A Duhlin, P Tripathi, A Camponesch, BT Porse, AG Rolink, H Nissbrandt, SJ Turley, H Carlsten, IL Mårtensson, MCI Karlsson, Å Tivesten Testosterone is an endogenous regulator of BAFF and splenic B cell number Nat Commun, 2018-05-25;9(1):2067. 2018-05-25 [PMID: 29802242] (Human)
• K James, C Chipeta, A Parker, S Harding, SJ Cockell, CS Gillespie, J Hallinan, F Barone, SJ Bowman, WF Ng, BA Fisher B-cell activity markers are associated with different disease activity domains in primary Sj�gren's syndrome Rheumatology (Oxford), 2018-07-01;0(0):. 2018-07-01 [PMID: 29608774] (Human)
• L Alvarez, L Riancho, J Calvo-Alén, M Lopez Hoyo, V Martinez-T Peripheral B-Cell Subset Distribution in Primary Antiphospholipid Syndrome Int J Mol Sci, 2018-02-16;19(2):. 2018-02-16 [PMID: 29462939] (Human)
• J Heremans, JE Garcia-Per, E Turro, SM Schlenner, I Casteels, R Collin, F de Zegher, D Greene, S Humblet-Ba, S Lesage, P Matthys, CJ Penkett, K Put, K Stirrups, C Thys, C Van Geet, E Van Nieuwe, C Wouters, I Meyts, K Freson, A Liston Abnormal differentiation of B cells and megakaryocytes in Roifman syndrome J. Allergy Clin. Immunol., 2018-01-31;0(0):. 2018-01-31 [PMID: 29391254] (Human)
• I Smets, B Fiddes, JE Garcia-Per, D He, K Mallants, W Liao, J Dooley, G Wang, S Humblet-Ba, B Dubois, A Compston, J Jones, A Coles, A Liston, M Ban, A Goris, S Sawcer Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells Brain, 2018-03-01;0(0):. 2018-03-01 [PMID: 29361022] (Human)
• Y Fu, L Wang, C Xie, K Zou, L Tu, W Yan, X Hou Comparison of non-invasive biomarkers faecal BAFF, calprotectin and FOBT in discriminating IBS from IBD and evaluation of intestinal inflammation Sci Rep, 2017-06-01;7(1):2669. 2017-06-01 [PMID: 28572616] (Human)
• S Wang, T Yang, J Wan, Y Zhang, Y Fan Elevated C-X-C motif ligand 13 and B-cell-activating factor levels in neuromyelitis optica during remission Brain Behav, 2017-03-10;7(4):e00648. 2017-03-10 [PMID: 28413701] (Human)
• MR Pranzatell, ED Tate, TJ Allison Case-control, exploratory study of cerebrospinal fluid chemokines/cytokines and lymphocyte subsets in childhood Tourette syndrome with positive streptococcal markers Cytokine, 2017-03-10;96(0):49-53. 2017-03-10 [PMID: 28288328] (Human)
• S Ajeganova, D Tesfa, H Hägglund, B Fadeel, I Vedin, AL Zignego, J Palmblad Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab Arthritis Res. Ther, 2017-03-07;19(1):44. 2017-03-07 [PMID: 28270182] (Human)
• I Parodis, C Sjöwall, A Jönsen, D Ramsköld, A Zickert, M Frodlund, A Sohrabian, L Arnaud, J Rönnelid, V Malmström, AA Bengtsson, I Gunnarsson Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus Autoimmun Rev, 2017-02-13;0(0):. 2017-02-13 [PMID: 28216072] (Human)
• P Gyllemark, P Forsberg, J Ernerudh, AJ Henningsso Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study J Neuroinflammation, 2017-02-01;14(1):27. 2017-02-01 [PMID: 28148307] (Human)
• M Puthenpara, L Federle, S Miante, A Zito, E Toffanin, S Ruggero, M Ermani, S Pravato, D Poggiali, P Perini, F Rinaldi, P Gallo BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset J Neuroinflammation, 2017-01-17;14(1):11. 2017-01-17 [PMID: 28095856] (Human)
• Bingru Lu Hepatitis B Virus e Antigen Regulates Monocyte Function and Promotes B Lymphocyte Activation Viral Immunol, 2016-12-15;0(0):. 2016-12-15 [PMID: 27976981]
• Shigeharu Fujieda Toll-like receptor ligands induce cytokine and chemokine production in human inner ear endolymphatic sac fibroblasts Auris Nasus Larynx, 2016-11-21;0(0):. 2016-11-21 [PMID: 27884591] (Human)
• Almut Meyer-Bahl Human Basophils Modulate Plasma Cell Differentiation and Maturation J. Immunol., 2016-11-16;0(0):. 2016-11-16 [PMID: 27852746] (Human)
• Serum B-cell activating factor predicts prognosis in nasal type, extranodal NK/T cell lymphoma Cytokine, 2016-09-24;88(0):196-198. 2016-09-24 [PMID: 27668971] (Human)
• A distinct plasmablast and na�ve B-cell phenotype in primary immune thrombocytopenia Haematologica, 2016-03-11;101(6):698-706. 2016-03-11 [PMID: 26969086] (Human)
• Borhis G, Burelout C, Chaoul N, Smith N, Goujard C, Meyer L, Paul S, Saoudin H, Hosmalin A, Gilbert C, Herbeuval J, Richard Y Plasmacytoid dendritic cells and myeloid cells differently contribute to BAFF over-expression during primary HIV infection. AIDS, 2016-01-28;30(0):365-376. 2016-01-28 [PMID: 26558721] (Human)
• Bornacelly , Adriana, Mercado , Dilia, Acevedo , Nathalie, Caraballo , Luis The strength of the antibody response to the nematode Ascaris lumbricoides inversely correlates with levels of B-Cell Activating Factor (BAFF). BMC Immunol, 2014-06-07;15(0):22. 2014-06-07 [PMID: 24906685] (Human)
• Neill , Daniel R, Saint , Gemma L, Bricio-Moreno , Laura, Fothergill , Joanne L, Southern , Kevin W, Winstanley , Craig, Christmas , Stephen, Slupsky , Joseph R, McNamara , Paul S, Kadioglu , Aras, Flanagan , Brian F The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa. PLoS ONE, 2014-05-21;9(5):e95892. 2014-05-21 [PMID: 24847941] (Human)
• Yang , Cuiling, Li , Na, Wang , Yawen, Zhang , Pingping, Zhu , Qianqian, Li , Fang, Han , Qunying, Lv , Yi, Yu , Ling, Wei , Ping, Liu , Zhengwen Serum levels of B-cell activating factor in chronic hepatitis B virus infection: association with clinical diseases. J Interferon Cytokine Res, 2014-05-08;34(10):787-94. 2014-05-08 [PMID: 24811691] (Human)
• Muller N, Schulte D, Hillebrand S, Turk K, Hampe J, Schafmayer C, Brosch M, von Schonfels W, Ahrens M, Zeuner R, Schroder J, Bluher M, Gutschow C, Freitag-Wolf S, Stelmach-Mardas M, Saggau C, Schreiber S, Laudes M B Lymphocyte Stimulator (BLyS) is expressed in human adipocytes in vivo and is related to obesity but not to insulin resistance. PLoS ONE, 2014-04-11;9(4):e94282. 2014-04-11 [PMID: 24728308] (Human)
• Scholzen A, Teirlinck A, Bijker E, Roestenberg M, Hermsen C, Hoffman S, Sauerwein R BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection. J Immunol, 2014-03-19;192(8):3719-29. 2014-03-19 [PMID: 24646735] (Human)
• Palanichamy A, Bauer J, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight J, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, Liesveld J, Sanz I, Baechler E, Kaplan M, Anolik J Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus. J Immunol, 2013-12-30;192(3):906-18. 2013-12-30 [PMID: 24379124] (Human)
• Jordan V. Price, David J. Haddon, Dodge Kemmer, Guillaume Delepine, Gil Mandelbaum, Justin A. Jarrell et al. Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus Journal of Clinical Investigation 2013-12-02 [PMID: 24270423] (Human)
• Giacomini E, Severa M, Rizzo F, Mechelli R, Annibali V, Ristori G, Riccieri V, Salvetti M, Coccia E IFN-beta therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients. Eur J Immunol, 2013-05-28;43(7):1963-72. 2013-05-28 [PMID: 23636665] (Human)
• Raffaghello L, Fuhlhuber V, Bianchi G, Conte M, Blaes F, Gambini C, Pistoia V Role of BAFF in Opsoclonus-Myoclonus syndrome, a bridge between cancer and autoimmunity. J Leukoc Biol, 2013-04-22;94(1):183-91. 2013-04-22 [PMID: 23610147] (Human)
• Pranzatelli , Michael, Tate , Elizabet, McGee , Nathan R, Travelstead , Anna L, Colliver , Jerry A, Ness , Jayne M, Ransohoff , Richard BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy. J Neuroinflammation, 2013-01-16;10(0):10. 2013-01-16 [PMID: 23324534] (Human)
• Pontikoglou C, Kastrinaki M, Klaus M, Kalpadakis C, Katonis P, Alpantaki K, Pangalis G, Papadaki H Study of the quantitative, functional, cytogenetic, and immunoregulatory properties of bone marrow mesenchymal stem cells in patients with B-cell chronic lymphocytic leukemia. Stem Cells Dev, 2013-02-01;22(9):1329-41. 2013-02-01 [PMID: 23249221] (Human)
• Saussine A, Tazi A, Feuillet S, Rybojad M, Juillard C, Bergeron A, Dessirier V, Bouhidel F, Janin A, Bensussan A, Bagot M, Bouaziz J Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels. PLoS ONE, 2012-08-22;7(8):e43588. 2012-08-22 [PMID: 22927996] (Human)
• Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival. PLoS ONE, 2012-07-09;7(7):e40620. 2012-07-09 [PMID: 22792388] (Human)
• Chaoul N, Burelout C, Peruchon S, van Buu B, Laurent P, Proust A, Raphael M, Garraud O, Le Grand R, Prevot S, Richard Y Default in plasma and intestinal IgA responses during acute infection by simian immunodeficiency virus. Retrovirology, 2012-05-25;9(0):43. 2012-05-25 [PMID: 22632376] (Human, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque))
• Ohmatsu H, Sugaya M, Miyagaki T, Suga H, Fujita H, Asano Y, Tada Y, Kadono T, Sato S BAFF levels are increased in lesional skin and sera in patients with cutaneous T-cell lymphoma. Br. J. Dermatol., 2012-07-05;167(2):359-67. 2012-07-05 [PMID: 22512719] (Human)
• B-cell activating factor levels in rheumatoid arthritis patients in response to treatment with biologics. J. Interferon Cytokine Res., 2012-04-17;32(7):338-40. 2012-04-17 [PMID: 22509979] (Human)
• Barbosa RR, Silva SP, Silva SL, Melo AC, Pedro E, Barbosa MP, Pereira-Santos MC, Victorino RM, Sousa AE Primary B-cell deficiencies reveal a link between human IL-17-producing CD4 T-cell homeostasis and B-cell differentiation. PLoS ONE, 2011-08-03;6(8):e22848. 2011-08-03 [PMID: 21826211] (Human)
• Sarantopoulos S, Stevenson KE, Kim HT Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease. Blood, 2010-11-19;117(7):2275-83. 2010-11-19 [PMID: 21097674] (Human)
• Kuzmina Z, Greinix HT, Weigl R, Kormoczi U, Rottal A, Frantal S, Eder S, Pickl WF Significant differences in B-cell subpopulations characterize patients with chronic graft-versus-host disease-associated dysgammaglobulinemia. Blood, 2010-11-09;117(7):2265-74. 2010-11-09 [PMID: 21063025] (Human)
• Sugalski JM, Rodriguez B, Moir S Peripheral blood B cell subset skewing is associated with altered cell cycling and intrinsic resistance to apoptosis and reflects a state of immune activation in chronic hepatitis C virus infection. J. Immunol., 2010-07-23;185(5):3019-27. 2010-07-23 [PMID: 20656924] (Human)
• Zarkhin V, Li L, Sarwal MM BAFF may modulate the rate of B-cell repopulation after rituximab therapy for acute renal transplant rejection. Transplantation, 2009-11-27;88(10):1229-30. 2009-11-27 [PMID: 19935379] (Human)
• Chauhan D, Singh AV, Brahmandam M, Carrasco R, Bandi M, Hideshima T, Bianchi G, Podar K, Tai YT, Mitsiades C, Raje N, Jaye DL, Kumar SK, Richardson P, Munshi N, Anderson KC Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target. Cancer Cell, 2009-10-06;16(4):309-23. 2009-10-06 [PMID: 19800576] (Human)
• Thompson SA, Jones JL, Cox AL, Compston DA, Coles AJ B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis. J. Clin. Immunol., 2009-09-10;30(1):99-105. 2009-09-10 [PMID: 19763798] (Human)
• Bloom D, Chang Z, Pauly K BAFF is increased in renal transplant patients following treatment with alemtuzumab. Am. J. Transplant., 2009-06-12;9(8):1835-45. 2009-06-12 [PMID: 19522878] (Human)
• Bojarska-Junak A, Hus I, Chocholska S, Wasik-Szczepanek E, Sieklucka M, Dmoszynska A, Rolinski J BAFF and APRIL expression in B-cell chronic lymphocytic leukemia: correlation with biological and clinical features. Leuk. Res., 2009-04-23;33(10):1319-27. 2009-04-23 [PMID: 19395025] (Human)
• Fuhlhuber V, Bick S, Kirsten A, Hahn A, Gerriets T, Tschernatsch M, Kaps M, Preissner KT, Blaes F, Altenkamper S Elevated B-cell activating factor BAFF, but not APRIL, correlates with CSF cerebellar autoantibodies in pediatric opsoclonus-myoclonus syndrome. J. Neuroimmunol., 2009-03-31;210(1):87-91. 2009-03-31 [PMID: 19339060] (Human)
• Nagel A, Podstawa E, Eickmann M, Muller HH, Hertl M, Eming R Rituximab mediates a strong elevation of B-cell-activating factor associated with increased pathogen-specific IgG but not autoantibodies in pemphigus vulgaris. J. Invest. Dermatol., 2009-03-12;129(9):2202-10. 2009-03-12 [PMID: 19282839] (Human)
• Takeda T, Sakurai Y, Tatsumi K, Kato J, Kasuda S, Yoshioka A, Shima M Elevation of B cell-activating factor belonging to the tumour necrosis factor [corrected] family (BAFF) in haemophilia A patients with inhibitor. Thromb. Haemost., 2009-02-01;101(2):408-10. 2009-02-01 [PMID: 19190830] (Human)
• Sarantopoulos S, Stevenson KE, Kim HT, Cutler CS, Bhuiya NS, Schowalter M, Ho VT, Alyea EP, Koreth J, Blazar BR, Soiffer RJ, Antin JH, Ritz J Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease. Blood, 2009-01-23;113(16):3865-74. 2009-01-23 [PMID: 19168788] (Human)
• Zdzisinska B, Bojarska-Junak A, Dmoszynska A, Kandefer-Szerszen M Abnormal cytokine production by bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells. Arch. Immunol. Ther. Exp. (Warsz.), 2008-05-30;56(3):207-21. 2008-05-30 [PMID: 18512025] (Human)
• Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392. 2008-04-14 [PMID: 18410958] (Human)
• Breitkreutz I, Raab MS, Vallet S, Hideshima T, Raje N, Chauhan D, Munshi NC, Richardson PG, Anderson KC Targeting MEK1/2 blocks osteoclast differentiation, function and cytokine secretion in multiple myeloma. Br. J. Haematol., 2007-10-01;139(1):55-63. 2007-10-01 [PMID: 17854307] (Human)
• Tai YT, Li XF, Breitkreutz I, Song W, Neri P, Catley L, Podar K, Hideshima T, Chauhan D, Raje N, Schlossman R, Richardson P, Munshi NC, Anderson KC Role of B-cell-activating factor in adhesion and growth of human multiple myeloma cells in the bone marrow microenvironment. Cancer Res., 2006-07-01;66(13):6675-82. 2006-07-01 [PMID: 16818641] (Human)

FAQs for BAFF/BLyS/TNFSF13B (DBLYS0B). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: TNFSF13B