Hu, Mu, RtApplications:
WB, ELISA, IHC, IHC-P, ICC/IFHost:
WB, B/N, ICC/IFHost:
Applications: WB, B/N
Host: Goat Polyclonal
CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. ITEM-4 antibody reacts with both mouse and human Fn14. It is useful for flow cytometric analysis.
|Product By Gene ID
- APO3 ligand
- tumor necrosis factor ligand superfamily member 12
- TNF-related weak inducer of apoptosis
- DR3LGTWEAKAPO3/DR3 ligand
- tumor necrosis factor (ligand) superfamily, member 12
Bioinformatics Tool for TWEAK/TNFSF12
Discover related pathways, diseases and genes to TWEAK/TNFSF12. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.