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1090-TW) inhibits proliferation in the the HT-29 human colon adenocarcinoma cell line in a dose-dependent manner (orange line). Activity elicited by Recombinant Human TWEAK/TNFSF12 (1 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human TWEAK/ TNFSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1090). The ND50 is typically 2-8 µg/mL." class="big_lightbox" target="_blank">
1090-TW) was serially diluted and captured by Mouse Anti-Human TWEAK/TNFSF12 Monoclonal Antibody (Catalog # MAB1090) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human TWEAK/TNFSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1090) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
1237-TW) inhibits proliferation in the the HT-29 human colon adenocarcinoma cell line in a dose-dependent manner (orange line). Activity elicited by Recombinant Mouse TWEAK/TNFSF12 (2 µg/mL) is neutralized (green line) by increasing concen-trations of Goat Anti-Mouse TWEAK/ TNFSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1237). The ND50 is typically 4-16 µg/mL." class="big_lightbox" target="_blank">
1237-TW) was serially diluted and captured by Rat Anti-Mouse TWEAK/TNFSF12 Monoclonal Antibody (Catalog # MAB1237) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Mouse TWEAK/TNFSF12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1237) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
CD266 is a 14 kD transmembrane protein known as TWEAK receptor (TWEAK-R) or fibroblast growth factor inducible 14 (Fn14). It is member 12A of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed at low levels in a variety of tissues, such as heart, placenta, lung, muscle, and pancreas. TWEAK-R binds TWEAK (CD255) and interacts with the cytoplasmic proteins TRAF1, 2, and 3. The engagement of Fn14 can induce cell death and may play a role in inflammation, hepatocyte growth, and liver neoplasia. ITEM-4 antibody reacts with both mouse and human Fn14. It is useful for flow cytometric analysis.
![Neutralization TWEAK/TNFSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/TWEAK_AF1090_Block_Neutralize_231.jpg)
![N/A TWEAK/TNFSF12 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_TWEAK_DY1090_ELISA_1569.jpg)
![N/A TWEAK/TNFSF12 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_TWEAK_DY1237_ELISA_1609.jpg)
![Bioactivity TWEAK/TNFSF12 [Unconjugated]](http://images.novusbio.com/fullsize/protein/TWEAK_1090-TW_656.jpg)
![Immunocytochemistry TWEAK/TNFSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/TWEAK_AF1090_Immunocytochemistry_6467.jpg)
![ELISA TWEAK/TNFSF12 Antibody [Unconjugated]](http://images.novusbio.com/images/af1090_human-tweak-tnfsf12-affinity-purified-polyclonal-ab-elisa-639201856338714265.jpg)
![SDS-Page TWEAK/TNFSF12 [Unconjugated]](http://images.novusbio.com/fullsize/protein/TWEAK_1090-TW_654.jpg)
