Tryptophan hydroxylase 2 Antibody

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Western Blot: Tryptophan hydroxylase 2 Antibody [NBP1-77556] - WB analysis of TPHZ in human stomach lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.19 mg/ml

Tryptophan hydroxylase 2 Antibody Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the human Tryptophan hydroxylase 2 protein (between residues 1-100) [UniProt Q8IWU9]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TPH2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 2 ug/ml
Application Notes
This Tryptophan hydroxylase 2 antibody is useful in Western blot, where a band is seen ~50 kDa.
Positive Control
Stomach Lysate (NB820-59260)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1.19 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Tryptophan hydroxylase 2 Antibody

  • ADHD7
  • EC 1.14.16
  • EC 1.14.16.4
  • FLJ37295
  • MGC138872
  • Neuronal tryptophan hydroxylase
  • NTPH
  • NTPHMGC138871
  • TPH2
  • tryptophan 5-hydroxylase 2
  • Tryptophan 5-monooxygenase 2
  • Tryptophan Hydroxylase 2

Background

TPH2 is a protein of the pterin dependent aromatic acid hydroxylase family. It catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. TPH2 is expressed predominantly in the central nervous system. Mutations in TPH2 gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-77556AF405
Alexa Fluor 488 Labeled NBP1-77556AF488
Alexa Fluor 647 Labeled NBP1-77556AF647
Alexa Fluor 700 Labeled NBP1-77556AF700
Biotin Labeled NBP1-77556B
DyLight 405 Labeled NBP1-77556V
DyLight 488 Labeled NBP1-77556G
DyLight 550 Labeled NBP1-77556R
DyLight 650 Labeled NBP1-77556C
HRP Labeled NBP1-77556H

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Bioinformatics

Gene Symbol TPH2
Entrez
Uniprot