5-HT1B Antibody

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Western Blot: 5-HT1B Antibody [NB100-56350] - Analysis of 5-HT1B in human brain lysate with anti-5-HT1BR pcAb (NB100-56350). A protein band of approximate molecular weight of 40-41kDa was detected.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

5-HT1B Antibody Summary

Immunogen
This antibody was generated by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 8-26 and 263-278 of rat 5-HT1BR (Accession number P28564)
Specificity
A 40-41 kDa band is detected.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HTR1B
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
Positive Control
Brain Lysate (NB820-59705)
Brain Lysate (NB820-59657)
Brain Lysate (NB820-59177)
Publications
Read Publication using
NB100-56350 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for 5-HT1B Antibody

  • 5HT1B
  • 5-HT1B
  • 5-HT1B5-HT-1B
  • 5HT1DB
  • 5-HT1DB
  • 5-hydroxytryptamine (serotonin) receptor 1B
  • HTR1B
  • HTR1D2
  • HTR1D2,5-hydroxytryptamine receptor 1B
  • HTR1DB
  • S12
  • S125-HT-1D-beta
  • Serotonin 1D beta receptor
  • Serotonin receptor 1B

Background

Serotonin (5-hydroxytryptamine, 5-HT), originally discovered as a serum factor plays important roles in regulating diverse biological processes in central and peripheral nervous systems, cardiovascular systems, and gastrointestinal systems. Molecular cloning studies have identified 5 receptors belonging to the 5-HT1 subtypes. These receptors are negatively coupled to adenylyl cyclase. Radioligand binding studies suggest the presence of 5-HT1B (formerly known as 5-HT1DbR) sites in substantia nigra, dorsal subiculum, globus pallidus, and superior collicum. The in situ hybridization studies show abundance of 5-HT1BR mRNA in CA1 pyramidal cells of hippocampus, Purkinje cells of cerebellum, olfactory tubercle, subthalamic nucleus and somewhat lower levels in the caudate-putamen, cortical areas, thalamic and hypothalamic nuclei.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for 5-HT1B Antibody (NB100-56350)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HTR1B
Entrez
Uniprot