TrkB Antibody (8D2E8) - BSA Free

Western Blot: TrkB Antibody (8D2E8) [NBP2-52523] - Analysis using NTRK2 mAb against HEK293 (1) and NTRK2 (AA: 207-339)-hIgGFc transfected HEK293 (2) cell lysate.

Western Blot: TrkB Antibody (8D2E8) [NBP2-52523] - Analysis using NTRK2 mAb against human NTRK2 (AA: 207-339) recombinant protein. (Expected MW is 40.6 kDa)

ELISA: TrkB Antibody (8D2E8) [NBP2-52523] - Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

• Reactivity: Hu
• Applications: WB, ELISA, CyTOF-ready
• Clone: 8D2E8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TrkB Antibody (8D2E8) - BSA Free Summary

• Immunogen: Purified recombinant fragment of human TrkB (AA: 207-339) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: NTRK2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • ELISA 1:10000
  • Western Blot 1:500-1:2000
• Application Notes: This antibody is Cytof ready.
• Theoretical MW: 92 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for TrkB Antibody (8D2E8) - BSA Free

• BDNF/NT-3 growth factors receptor
• EC 2.7.10
• EC 2.7.10.1
• GP145-TrkB
• Neurotrophic tyrosine kinase receptor type 2
• neurotrophic tyrosine kinase, receptor, type 2
• NTRK2
• TrkB tyrosine kinase
• TrkB
• trk-B
• TRKBBDNF-tropomyosine receptor kinase B
• tyrosine kinase receptor B

Background

TrkB is a tyrosine-protein kinase receptor involved in the development and/or maintenance of the nervous system. TrkB is a receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5, but not nerve growth factor (NGF). The major substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TrkB Antibody (NBP2-52523)(1)

Publication using NBP2-52523

• Ferreira LAM, Bezerra MADS, Kawasaki-Oyama RS et al. Effect of ZEB1 Associated with microRNAs on Tumor Stem Cells in Head and Neck Cancer International journal of molecular sciences 2023-03-21 [PMID: 36982993] (WB, Human)

Bioinformatics

• Gene Symbol: NTRK2