Western Blot: TMEM97 Antibody [NBP1-30436] - Analysis of TMEM97 in HeLa whole cell extracts.
Immunocytochemistry/ Immunofluorescence: TMEM97 Antibody [NBP1-30436] - Immunocytochemical analysis in HeLa cells
Immunocytochemistry/ Immunofluorescence: TMEM97 Antibody [NBP1-30436] - Saining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue).
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 30% glycerol
0.1% Sodium Azide
Immunogen affinity purified
Western Blot 2 ug/ml
This TMEM97 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen at ~24 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
24 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Human. Predicted to react with monkey based on 100% sequence homology.
Alternate Names for TMEM97 Antibody
transmembrane protein 97
TMEM97 (transmembrane protein 97 or protein MAC30) is a member of IGFBP/insulin-like growth factor-binding protein family and is implicated in several biological processes wherein it acts through its regulatory effects on IGF activity. It is a multi-pass membrane protein which is localized in nuclear and cell membranes, RER and lysosomes, and is expressed in several normal tissues including brain, lung, heart, skeletal muscles, testis, ovary, and pregnant uterus. TMEM97 was originally identified as overexpressed in meningiomas, however, later it was found to exhibit altered expression in different types of cancers. The absence or downregulation of TMEM97 expression in pancreatic cancer suggests that it may acts as a tumor suppressor in pancreatic cancer. Contrastingly, its expression is stronger in breast, esophageal, stomach, colon, and oral squamous cell cancers than the corresponding normal tissues. Its physiological function is largely unknown, however, it has been suggested to implicate in cellular proliferation/differentiation and regulation of cholesterol homeostasis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
First Commercial TMEM97 Antibody Launched We at Novus Biologicals recently created excitement when we added TMEM97 antibody to our database. We are the first antibody suppliers to offer a product targeted to TMEM97.TMEM97 (transmembrane protein 97, also known as MAC30) is a multi-cross tran... Read full blog post.