TMEM97 Antibody [DyLight 405]

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Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 405

TMEM97 Antibody [DyLight 405] Summary

Immunogen
Synthetic peptide made to an internal portion of the human TMEM97 protein (within residues 105-155. [Swiss-Prot# Q5BJF2]
Localization
Membrane; Multi-pass membrane protein
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM97
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This TMEM97 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen at ~24 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human. Predicted to react with monkey based on 100% sequence homology.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TMEM97 Antibody [DyLight 405]

  • MAC30Protein MAC30
  • transmembrane protein 97

Background

TMEM97 (transmembrane protein 97 or protein MAC30) is a member of IGFBP/insulin-like growth factor-binding protein family and is implicated in several biological processes wherein it acts through its regulatory effects on IGF activity. It is a multi-pass membrane protein which is localized in nuclear and cell membranes, RER and lysosomes, and is expressed in several normal tissues including brain, lung, heart, skeletal muscles, testis, ovary, and pregnant uterus. TMEM97 was originally identified as overexpressed in meningiomas, however, later it was found to exhibit altered expression in different types of cancers. The absence or downregulation of TMEM97 expression in pancreatic cancer suggests that it may acts as a tumor suppressor in pancreatic cancer. Contrastingly, its expression is stronger in breast, esophageal, stomach, colon, and oral squamous cell cancers than the corresponding normal tissues. Its physiological function is largely unknown, however, it has been suggested to implicate in cellular proliferation/differentiation and regulation of cholesterol homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TMEM97 Antibody (NBP1-30436V) (0)

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Secondary Antibodies

 

Isotype Controls

Additional TMEM97 Products

Bioinformatics Tool for TMEM97 Antibody (NBP1-30436V)

Discover related pathways, diseases and genes to TMEM97 Antibody (NBP1-30436V). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TMEM97 Antibody (NBP1-30436V)

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Pathways for TMEM97 Antibody (NBP1-30436V)

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Research Areas for TMEM97 Antibody (NBP1-30436V)

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Blogs on TMEM97.

First Commercial TMEM97 Antibody Launched
We at Novus Biologicals recently created excitement when we added TMEM97 antibody to our database. We are the first antibody suppliers to offer a product targeted to TMEM97.TMEM97 (transmembrane protein 97, also known as MAC30) is a multi-cross tran...  Read full blog post.

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Bioinformatics

Gene Symbol TMEM97