Tissue alpha-L-Fucosidase/FUCA1 Antibody

Western Blot: Tissue alpha-L-Fucosidase/FUCA1 Antibody [H00002517-D01P] - Analysis of FUCA1 expression in mouse brain.

Western Blot: Tissue alpha-L-Fucosidase/FUCA1 Antibody [H00002517-D01P] - Analysis of FUCA1 expression in human liver.

Western Blot: Tissue alpha-L-Fucosidase/FUCA1 Antibody [H00002517-D01P] - Analysis of FUCA1 expression in transfected 293T cell line by FUCA1 polyclonal antibody.Lane 1: FUCA1 transfected lysate(53.20 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Tissue alpha-L-Fucosidase/FUCA1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: FUCA1 (AAH17338.1, 1 a.a. - 461 a.a.) full-length human protein. MRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
• Specificity: FUCA1 - fucosidase, alpha-L- 1, tissue,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: FUCA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Tissue alpha-L-Fucosidase/FUCA1 Antibody

• Alpha-L-fucosidase 1
• Alpha-L-fucosidase I
• Alpha-L-fucoside fucohydrolase 1
• EC 3.2.1
• EC 3.2.1.51
• FUCA
• FUCA1
• fucosidase, alpha-L- 1, tissue
• Tissue alphaLFucosidase
• Tissue alpha-L-Fucosidase

Background

Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids (Occhiodoro et al., 1989 [PubMed 2803312]). At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis (MIM 230000), and that in plasma, FUCA2 (MIM 136820).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FUCA1
• Entrez:
  • 2517(Human)
• Uniprot:
  • AAH17338.1(Human)