TIM-1/KIM-1/HAVCR Antibody (RMT1-4) [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
RMT1-4
Clonality
Monoclonal
Host
Rat
Conjugate
Biotin

TIM-1/KIM-1/HAVCR Antibody (RMT1-4) [Biotin] Summary

Immunogen
The immunogen for this antibody was Purified TIM1.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Rat
Gene
HAVCR1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
Flow Cytometry For immunofluorescent staining, the suggested use of this reagent is: 0.5 microgram per one million cells in 100 microliter volume.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Purity
Protein A or G purified

Alternate Names for TIM-1/KIM-1/HAVCR Antibody (RMT1-4) [Biotin]

  • CD365
  • HAVCR1
  • HAVCR-1
  • HAVCRT cell immunoglobin domain and mucin domain protein 1
  • hepatitis A virus cellular receptor 1
  • Kidney injury molecule 1
  • KIM1
  • KIM-1
  • T-cell immunoglobulin and mucin domain-containing protein 1
  • TIM1
  • TIM-1
  • TIM-1TIM
  • TIM1TIMD-1
  • TIMD1T-cell membrane protein 1

Background

The RMT1-4 monoclonal antibody reacts with mouse TIM-1, a member of newly identified T cell immunoglobulin domain, mucin-like domain (TIM) gene family. TIM family of proteins are transmembrane proteins expressed by CD4 T cells. Recent studies demonstrate that the TIM family, particularly TIM-1, plays a critical role in immune responses that regulate the development of atopic diseases. Human TIM-1 is a functional receptor for hepatitis A virus (HAV). In humans, certain polymorphic variants of TIM-1 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV). Activation of T cells through TIM-1 by HAV or by its natural ligand may affect T cell differentiation and the development of Th2-driven allergic inflammatory responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for TIM-1/KIM-1/HAVCR Antibody (NBP1-43541)

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Diseases for TIM-1/KIM-1/HAVCR Antibody (NBP1-43541)

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Bioinformatics

Gene Symbol HAVCR1
Entrez