Thyroid Peroxidase Antibody (TPO28)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IA, S-ELISA
Clone
TPO28
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Thyroid Peroxidase Antibody (TPO28) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with human thyroid peroxidase.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TPO
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunoassay
  • Sandwich ELISA 1:100-1:2000
Application Notes
ELISA, ImmunoAssay and WesterBlot Detection of human TPO (both native and recombinant).NBP1-50812, NBP1-50811, NBP1-50812, and NBP1-50813 are working in direct ELISA and sandwich immunoassays. Recommended pairs for sandwich immunoassays (capture-detection): NBP1-50811(Capture)-NBP1-50813(Detection) NBP1-50811 and NBP1-50812 can be applied for Western blotting detection of human TPO (both native and recombinant).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Thyroid Peroxidase Antibody (TPO28)

  • EC 1.11.1
  • MSA
  • TDH2A
  • thyroid microsomal antigen
  • thyroid peroxidase
  • thyroperoxidase
  • TPXEC 1.11.1.8

Background

Thyroid Peroxidase (TPO) plays a central role in thyroid gland function. The enzyme catalyzes two important reactions of thyroid hormone synthesis: the iodination of tyrosine residues in thyroglobulin and phenoxy ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. A defect in this gene is thought to cause several disorders of thyroid hormonogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TPO