Human TIMP-1 Quantikine ELISA Kit Summary
The Quantikine Human TIMP-1 Immunoassay is a 3.5 hour solid phase ELISA designed to measure TIMP-1 concentrations in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human TIMP-1 and antibodies raised against the recombinant factor. It has been shown to quantitate recombinant human TIMP-1 accurately. Results obtained using natural TIMP-1 showed linear... curves that were parallel to the standard curve obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural TIMP-1.
Natural and recombinant human TIMP-1
Solid Phase Sandwich ELISA
Interference observed with 1 or more available related molecules.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human TIMP-1 Quantikine ELISA Kit
- Collagenase inhibitor
- collagenase inhibitor)
- erythroid potentiating activity
- Erythroid-potentiating activity
- Fibroblast collagenase inhibitor
- metalloproteinase inhibitor 1
- TIMP metallopeptidase inhibitor 1
- TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
- Tissue inhibitor of metalloproteinases 1
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
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Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
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Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for TIMP-1 (DTM100). (Showing 1 - 1 of 1 FAQs).
wondering what the difference is between your quantikine and duo set elisas?
- Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
Other Available Formats
Additional TIMP-1 Products
Bioinformatics Tool for TIMP-1 (DTM100)
Discover related pathways, diseases and genes to TIMP-1 (DTM100). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on TIMP-1