Human TIMP-1 Quantikine ELISA Kit



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Reactivity HuSpecies Glossary
Applications ELISA

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Human TIMP-1 Quantikine ELISA Kit Summary

The Quantikine Human TIMP-1 Immunoassay is a 3.5 hour solid phase ELISA designed to measure TIMP-1 concentrations in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human TIMP-1 and antibodies raised against the recombinant factor. It has been shown to quantitate recombinant human TIMP-1 accurately. Results obtained using natural TIMP-1 showed linear... curves that were parallel to the standard curve obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural TIMP-1.
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Natural and recombinant human TIMP-1
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
Interference observed with 1 or more available related molecules.
Read Publications using DTM100.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human TIMP-1 Quantikine ELISA Kit

  • CLGI
  • Collagenase inhibitor
  • collagenase inhibitor)
  • EPO
  • erythroid potentiating activity
  • Erythroid-potentiating activity
  • Fibroblast collagenase inhibitor
  • FLJ90373
  • HCI
  • metalloproteinase inhibitor 1
  • TIMP metallopeptidase inhibitor 1
  • TIMP1
  • TIMP-1
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • Tissue inhibitor of metalloproteinases 1


TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for TIMP-1 (DTM100)(96)

We have publications tested in 3 confirmed species: Human, Hamster, Rabbit.

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Showing Publications 1 - 10 of 96. Show All 96 Publications.
Publications using DTM100 Applications Species
Moon, CE;Kim, CH;Jung, JH;Cho, YJ;Choi, KY;Han, K;Seo, KY;Lee, HK;Ji, YW; Integrated Analysis of Transcriptome and Proteome of the Human Cornea and Aqueous Humor Reveal Novel Biomarkers for Corneal Endothelial Cell Dysfunction International journal of molecular sciences 2023-10-19 [PMID: 37895034] (Human) Human
R Ishihara, T Oda, Y Murakami, I Matsumura, S Watanabe, Y Asao, Y Masuda, N Gotoh, T Kasamatsu, H Takei, N Kobayashi, N Sasaki, T Saitoh, H Murakami, H Handa Myeloma Microenvironmental TIMP1 Induces the Invasive Phenotype in Fibroblasts to Modulate Disease Progression International Journal of Molecular Sciences, 2023-01-22;24(3):. 2023-01-22 [PMID: 36768545] (Human) Human
I Tsomidis, G Notas, C Xidakis, A Voumvourak, DN Samonakis, M Koulentaki, E Kouroumali Enzymes of Fibrosis in Chronic Liver Disease Biomedicines, 2022-12-08;10(12):. 2022-12-08 [PMID: 36551935] (Human) Human
N Nasiri-Ans, E Spilioti, I Kyrou, V Kalotychou, A Chatzigeor, D Sanoudou, K Dahlman-Wr, HS Randeva, AG Papavassil, P Moutsatsou, E Kassi Estrogen Receptor Subtypes Elicit a Distinct Gene Expression Profile of Endothelial-Derived Factors Implicated in Atherosclerotic Plaque Vulnerability International Journal of Molecular Sciences, 2022-09-19;23(18):. 2022-09-19 [PMID: 36142876] (Human) Human
DL Frey, C Bridson, S Dittrich, SY Graeber, M Stahl, S Wege, F Herth, O Sommerburg, C Schultz, A Dalpke, MA Mall, S Boutin Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis Frontiers in Microbiology, 2022-05-13;13(0):885822. 2022-05-13 [PMID: 35633718] (Human) Human
M Smeda, KM Galler, M Woelflick, A Rosendahl, C Moehle, B Lenhardt, W Buchalla, M Widbiller Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells International Journal of Molecular Sciences, 2022-02-27;23(5):. 2022-02-27 [PMID: 35269758] (Human) Human
H Huang, Q Lin, X Dai, J Chen, Z Bai, X Li, F Fang, Y Li Derivation and validation of urinary TIMP-1 for the prediction of acute kidney injury and mortality in critically ill children Journal of Translational Medicine, 2022-02-23;20(1):102. 2022-02-23 [PMID: 35197070] (Human) Human
ML Brown Lobb, AT Slominski, KA Hasty, S Zhang, DD Miller, W Li, TK Kim, Z Janjetovic, RC Tuckey, IO Scott, LK Myers, AE Postlethwa Modulation by 17,20S(OH)2pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis International Journal of Molecular Sciences, 2021-12-29;23(1):. 2021-12-29 [PMID: 35008794] (Human) Human
J Udzik, A Waszczyk, K Safranow, A Biskupski, K Majer, S Kwiatkowsk, E Kwiatkowsk Assessment and Prognosis in CSA-AKI Using Novel Kidney Injury Biomarkers: A Prospective Observational Study Biology, 2021-08-24;10(9):. 2021-08-24 [PMID: 34571700] (Human) Human
K Moriya, N Nishimura, T Namisaki, H Takaya, Y Sawada, H Kawaratani, K Kaji, N Shimozato, S Sato, M Furukawa, A Douhara, T Akahane, A Mitoro, J Yamao, H Yoshiji Zinc Administration and Improved Serum Markers of Hepatic Fibrosis in Patients with Autoimmune Hepatitis Journal of Clinical Medicine, 2021-06-02;10(11):. 2021-06-02 [PMID: 34199421] (Human) Human
Show All 96 Publications.

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Gene Symbol TIMP1