SOX4 Antibody

Western Blot: SOX4 Antibody [H00006659-A01] - WB analysis of 36.23 kDa SOX4 partial recombinant protein (NP_003098, 45 a.a. ~ 136 a.a) with GST tag using mouse polyclonal SOX4 antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated

SOX4 Antibody Summary

• Immunogen: SOX4 (NP_003098, 45 a.a. - 136 a.a.) partial recombinant protein with GST tag. KADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKS
• Specificity: SOX4 - SRY (sex determining region Y)-box 4
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SOX4
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: The quality control of this antibody is limited to WB on the immunizing protein. It has been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 50 % glycerol
• Preservative: No Preservative
• Purity: Unpurified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SOX4 Antibody

• ecotropic viral integration site 16
• EVI16
• SRY (sex determining region Y)-box 4
• SRY-related HMG-box gene 4
• transcription factor SOX-4

Background

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SOX4 Antibody (H00006659-A01)(1)

Publication using H00006659-A01

• Grau L, Luque-Garcia JL, Gonzalez-Peramato P et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS One. 2013-01-01 [PMID: 23308193] (Human)

Bioinformatics

• Gene Symbol: SOX4
• Entrez:
  • 6659(Human)
• OMIM:
  • 184430(Human)
• Uniprot:
  • NP_003098(Human)