SOX4 Products

Description

SOX4 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.

Bioinformatics

Uniprot	Q06945 Human
Product By Gene ID	6659
Alternate Names	ecotropic viral integration site 16 EVI16 SRY (sex determining region Y)-box 4 SRY-related HMG-box gene 4 transcription factor SOX-4

Research Areas for SOX4

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Stem Cell Markers

Related SOX4 Blog Posts

Check out the latest blog posts on SOX4.

Bad news for stomach cancer: BAMBI protein inhibits gastric carcinoma via TGF-beta/epithelial-mesenchymal transition signaling By Jamshed Arslan Pharm.D. Gastric carcinoma is the second leading cause of cancer-related deaths worldwide. One of the key features of gastric carcinoma is acidosis, which promotes growth and metastasis of gastric ...    Read more.

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