SOS2 Antibody [Allophycocyanin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Allophycocyanin

SOS2 Antibody [Allophycocyanin] Summary

• Immunogen: E. coli-derived recombinant human SOS2
  Met1-Ser384
  Accession # Q07890
• Specificity: Detects human SOS2 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SOS2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for SOS2 Antibody [Allophycocyanin]

• FLJ25596
• guanine nucleotide exchange factor
• guanine nucleotide releasing factor
• son of sevenless (Drosophilia) homolog 2
• son of sevenless homolog 2 (Drosophila)
• son of sevenless homolog 2
• SOS2
• SOS-2

Background

SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOS2