SLC31A1/CTR1 Antibody [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Xp, ZeSpecies Glossary
Applications WB, ICC/IF, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 488

SLC31A1/CTR1 Antibody [DyLight 488] Summary

Immunogen
A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [UniProt# O15431]
Localization
Cell Membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC31A1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This SLC31A1/CTR1 antibody is useful for Immunocytochemistry/Immunofluorescence, and Immunohistochemistry-paraffin embedded sections..

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SLC31A1/CTR1 Antibody [DyLight 488]

  • Copper transporter 1
  • COPT1high affinity copper uptake protein 1
  • CTR1MGC75487
  • hCTR1copper transport 1 homolog
  • solute carrier family 31 (copper transporters), member 1
  • Solute carrier family 31 member 1

Background

The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SLC31A1/CTR1 Antibody (NB100-402G) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NB100-402B
DyLight 550 Labeled NB100-402R
DyLight 650 Labeled NB100-402C
HRP Labeled NB100-402H

Additional SLC31A1/CTR1 Products

Bioinformatics Tool for SLC31A1/CTR1 Antibody (NB100-402G)

Discover related pathways, diseases and genes to SLC31A1/CTR1 Antibody (NB100-402G). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for SLC31A1/CTR1 Antibody (NB100-402G)

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Research Areas for SLC31A1/CTR1 Antibody (NB100-402G)

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Blogs on SLC31A1/CTR1.

SLC31A1/CTR1 - a copper transporter with important implications for platinum-based chemotherapy
Copper is an essential micronutrient that serves as a cofactor in numerous biological processes, but can be toxic when present in excess. Because of this, cells must tightly maintain copper levels. This includes balance between import and export of...  Read full blog post.

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Bioinformatics

Gene Symbol SLC31A1