SH3BP2 Antibody - BSA Free

Western Blot: SH3BP2 Antibody [NBP3-30802] - Western blot analysis using anti-3BP2 at 10 ug/ml on recombinant full length 3BP2 protein (1), 3BP2 protein inus the PH domain (2), 3BP2 protein minus the PR domain (3) and 3BP2 protein minus the SH2 domain (4).

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Unconjugated
• Format: BSA Free

SH3BP2 Antibody - BSA Free Summary

• Immunogen: Antibody developed using SH2 domain of the SH3BP2 protein fused to GST.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: SH3BP2
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2..

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for SH3BP2 Antibody - BSA Free

• Abl-SH3 binding protein 2
• Cherubism
• CRBM
• CRPM
• FLJ42079
• FLJ54978,3BP-2,3BP2
• RES4-23
• SH3 domain-binding protein 2
• SH3-domain binding protein 2
• TNFAIP3 interacting protein 2

Background

The protein encoded by the SH3BP2 gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SH3BP2