SH2D1A Antibody - BSA Free

Western Blot: SH2D1A Antibody [NBP3-30818] - Western blot analysis using SAP antibody on NK-92 cell lysate at 10ug/ml).

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SH2D1A Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SH2D1A Antibody - BSA Free (NBP3-30818) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Full-length recombinant SH2D1A protein
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SH2D1A
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot : 5-10 ug/ml
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.08% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for SH2D1A Antibody - BSA Free

• DSHP
• DSHPLYP
• Duncan disease SH2-protein
• EBVS
• FLJ92177
• IMD5
• LYP
• MTCP1
• SAP/SH2D1A
• SAPlymphoproliferative syndrome
• SH2 domain containing 1A
• SH2 domain-containing protein 1A
• SH2D1A
• signaling lymphocyte activation molecule-associated protein
• Signaling lymphocytic activation molecule-associated protein
• SLAM associated protein/SH2 domain protein 1A
• SLAM-associated protein
• T cell signal transduction molecule SAP
• T-cell signal transduction molecule SAP
• XLP
• XLPD
• XLPDFLJ18687
• XLPSH2 domain protein 1A

Background

The cytoplasmic protein encoded by the SH2D1A gene plays an essential role in controlling EBV infection. It is expressed in T and NK cells, but not in B cells or in granulocytes. SH2D1A is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD)also known as Duncan disease. XLPD is characterized by an immunodeficiency following Epstein-Barr virus (EBV)infection. Symptoms include fatal mononucleosis, hypogammaglobulinemia, pancytopenia or malignant lymphoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SH2D1A